adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 21 - 30 of 38 in total
Gene ID Gene Symbol Description Source
4638 MYLK myosin light chain kinase
4879 NPPB natriuretic peptide B
5054 SERPINE1 serpin family E member 1
5320 PLA2G2A phospholipase A2 group IIA
5328 PLAU plasminogen activator, urokinase
6439 SFTPB surfactant protein B
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
6648 SOD2 superoxide dismutase 2
6915 TBXA2R thromboxane A2 receptor
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11596 Ager advanced glycosylation end product-specific receptor
11699 Ambp alpha 1 microglobulin/bikunin precursor
12266 C3 complement component 3
12267 C3ar1 complement component 3a receptor 1
12273 C5ar1 complement component 5a receptor 1
14066 F3 coagulation factor III
14726 Pdpn podoplanin
15139 Hc hemolytic complement
15894 Icam1 intercellular adhesion molecule 1
16153 Il10 interleukin 10
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
84007 C3ar1 complement C3a receptor 1
113959 C5ar1 complement C5a receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
192155 Sftpb surfactant protein B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024