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acute leukemia
Summary
- Synonym
-
- Stem cell Leukemia
- Stem cell leukaemia
- Definition
- A lymphoid leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity producing large numbers of white blood cells to be produced and enter the blood stream.
- Super Class
- lymphoid leukemia
External Links
- Disease Ontology
- DOID:12603
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1543 | CYP1A1 | cytochrome P450 family 1 subfamily A member 1 | |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 | |
| 1576 | CYP3A4 | cytochrome P450 family 3 subfamily A member 4 | |
| 1577 | CYP3A5 | cytochrome P450 family 3 subfamily A member 5 | |
| 1604 | CD55 | CD55 molecule (Cromer blood group) | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 2526 | FUT4 | fucosyltransferase 4 | |
| 3251 | HPRT1 | hypoxanthine phosphoribosyltransferase 1 | |
| 3417 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 3418 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P12821 | Angiotensin-converting enzyme | |
| P13591 | Neural cell adhesion molecule 1 | |
| P13611 | Versican core protein | |
| P16442 | Histo-blood group ABO system transferase | |
| P16581 | E-selectin | |
| P20138 | Myeloid cell surface antigen CD33 | |
| P20273 | B-cell receptor CD22 | |
| P20815 | Cytochrome P450 3A5 | |
| P22083 | Alpha-(1,3)-fucosyltransferase 4 |
