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cytochrome P450 family 1 subfamily A member 1

Summary

Gene Symbol

CYP1A1

Aliases

CP11
P1-450
P450-C
P450DX

Organism

Homo sapiens (human)

External Links

NCBI Gene

1543

HGNC

2595

KEGG Gene ID

hsa:1543

PubChem

1543

Alliance of Genome Resources

HGNC:2595

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Fatty acid metabolism
Glycoprotein
Heme
Lipid metabolism
Lyase
Microsome
Mitochondrion inner membrane
Monooxygenase
Proteomics identification
Reference proteome
Steroid biosynthesis

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P04798	Cytochrome P450 form 6 Cytochrome P450-C Cytochrome P450-P1 Hydroperoxy icosatetraenoate dehydratase
E7EMT5
A0N0X8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 46 in total

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GO Term	Evidence Code	PMID
response to arsenic-containing substance	IEA
lipid hydroxylation	IDA	14559847
cellular response to copper ion	IEA
response to nematode	IEA
steroid metabolic process	IDA	14559847

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

secondary metabolic process [inference]

toxin metabolic process [inference]

insecticide metabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

xenobiotic metabolic process

insecticide metabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

toxin metabolic process [inference]

insecticide metabolic process

cellular alkene metabolic process [inference]

ethylene metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

heterocycle metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

vitamin D metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule catabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

lipid metabolic process [inference]

steroid metabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

flavonoid metabolic process

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

hydrocarbon metabolic process [inference]

olefin metabolic process [inference]

cellular alkene metabolic process [inference]

ethylene metabolic process

olefinic compound metabolic process [inference]

arachidonic acid metabolic process [inference]

retinol metabolic process

olefin metabolic process [inference]

cellular alkene metabolic process [inference]

ethylene metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organonitrogen compound metabolic process [inference]

amine metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

xenobiotic metabolic process

insecticide metabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

toxin metabolic process [inference]

insecticide metabolic process

cellular alkene metabolic process [inference]

ethylene metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

heterocycle metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

reproductive process [inference]

multicellular organismal reproductive process [inference]

maternal process involved in parturition

multicellular organismal process [inference]

tissue remodeling

developmental process [inference]

anatomical structure development [inference]

tube development [inference]

digestive tract development

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

camera-type eye development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to nematode

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to food

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to increased oxygen levels [inference]

response to hyperoxia

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to toxic substance [inference]

response to herbicide

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to organic cyclic compound [inference]

cellular response to organic cyclic compound

response to phenylpropanoid [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to diphenyl ether

response to polycyclic arene [inference]

response to 3-methylcholanthrene

response to 2,3,7,8-tetrachlorodibenzodioxine

response to lipid [inference]

response to ether [inference]

response to diphenyl ether

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to ketone [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to inorganic substance [inference]

response to metal ion [inference]

response to iron ion [inference]

response to iron(III) ion

response to copper ion [inference]

cellular response to copper ion

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to ether [inference]

response to diphenyl ether

response to ketone [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to salt [inference]

response to iron(III) ion

response to Aroclor 1254

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IBA
endoplasmic reticulum membrane	TAS
mitochondrial inner membrane	ISS
mitochondrion	HTP	34800366

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

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GO Term	Evidence Code	PMID
arachidonic acid monooxygenase activity	IDA	15041462
Hsp90 protein binding	ISS
long-chain fatty acid omega-1 hydroxylase activity	IDA	18577768
vitamin D 24-hydroxylase activity	IDA	15546903
demethylase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

monooxygenase activity

arachidonic acid monooxygenase activity

steroid hydroxylase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

flavonoid 3'-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

fatty acid omega-hydroxylase activity [inference]

long-chain fatty acid omega-hydroxylase activity

vitamin D 24-hydroxylase activity

oxidoreductase activity, acting on diphenols and related substances as donors

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

arachidonic acid monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

flavonoid 3'-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

fatty acid omega-hydroxylase activity [inference]

long-chain fatty acid omega-hydroxylase activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

hydroperoxy icosatetraenoate dehydratase activity

demethylase activity

binding [inference]

protein binding

enzyme binding

heat shock protein binding [inference]

protein-folding chaperone binding [inference]

Hsp70 protein binding

small molecule binding [inference]

oxygen binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome p450

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

KEGG BRITE Database

Orthology

K07408

Name

cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]

References

Rhea

RHEA:17149

an organic molecule + O₂

H₂O + H⁺ + an alcohol

Enzyme

1.14.14.1

PMID

RHEA:37947

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

RHEA:55556

a hydroperoxyeicosatetraenoate

an oxoeicosatetraenoate + H₂O

Enzyme

4.2.1.152

PMID

RHEA:48636

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

H₂O + 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

RHEA:37935

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

RHEA:37943

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

RHEA:37927

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050083	Keshan disease	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:10892	hypospadias	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:114	heart disease	Alliance of Genome Resources
DOID:11612	polycystic ovary syndrome	Alliance of Genome Resources
DOID:11836	clubfoot	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	13076		MGI:88588	MOUSE61937
Rattus norvegicus	24296		RGD:2458	RATNO42132
Danio rerio	140634		ZFIN:ZDB-GENE-011219-1	DANRE14017
Bos taurus	282870			BOVIN16656
Sus scrofa	403103			PIGXX32054
Pan troglodytes	453744	9598_0:003f15		PANTR10801
Meleagris gallopavo	664714			MELGA02987
Macaca mulatta	678694			MACMU41026
Monodelphis domestica	100029871			MONDO06635
Xenopus laevis	100036775		Xenbase:XB-GENE-990178

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements