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cytochrome P450 family 1 subfamily A member 1

Summary

Gene Symbol

CYP1A1

Aliases

CP11
P1-450
P450-C
P450DX

Organism

Homo sapiens (human)

External Links

NCBI Gene

1543

HGNC

2595

KEGG Gene ID

hsa:1543

PubChem

1543

Alliance of Genome Resources

HGNC:2595

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Fatty acid metabolism
Glycoprotein
Heme
Lipid metabolism
Lyase
Microsome
Mitochondrion inner membrane
Monooxygenase
Proteomics identification
Reference proteome
Steroid biosynthesis

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P04798	Cytochrome P450 form 6 Cytochrome P450-C Cytochrome P450-P1 Hydroperoxy icosatetraenoate dehydratase
E7EMT5
A0N0X8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 47 in total

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GO Term	Evidence Code	PMID
response to hypoxia	IEA
long-chain fatty acid metabolic process	IDA	18577768
lipid hydroxylation	IDA	14559847
fatty acid metabolic process	IDA	15041462
steroid biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

secondary metabolic process [inference]

toxin metabolic process [inference]

insecticide metabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

xenobiotic metabolic process

insecticide metabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

toxin metabolic process [inference]

insecticide metabolic process

cellular alkene metabolic process [inference]

ethylene metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

heterocycle metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

vitamin D metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule catabolic process [inference]

dibenzo-p-dioxin catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

lipid metabolic process [inference]

steroid metabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

flavonoid metabolic process

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

hydrocarbon metabolic process [inference]

olefin metabolic process [inference]

cellular alkene metabolic process [inference]

ethylene metabolic process

olefinic compound metabolic process [inference]

arachidonic acid metabolic process [inference]

retinol metabolic process

olefin metabolic process [inference]

cellular alkene metabolic process [inference]

ethylene metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organonitrogen compound metabolic process [inference]

amine metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

steroid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

phenol-containing compound metabolic process

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

xenobiotic metabolic process

insecticide metabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

toxin metabolic process [inference]

insecticide metabolic process

cellular alkene metabolic process [inference]

ethylene metabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

dibenzo-p-dioxin catabolic process

xenobiotic catabolic process [inference]

dibenzo-p-dioxin catabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

hydrogen peroxide biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

long-chain fatty acid metabolic process

arachidonic acid metabolic process [inference]

long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

diterpenoid biosynthetic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

lipid modification [inference]

lipid hydroxylation

heterocycle metabolic process [inference]

coumarin metabolic process

dibenzo-p-dioxin metabolic process [inference]

dibenzo-p-dioxin catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process

heterocycle catabolic process [inference]

dibenzo-p-dioxin catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

reactive oxygen species biosynthetic process [inference]

hydrogen peroxide biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

reproductive process [inference]

multicellular organismal reproductive process [inference]

maternal process involved in parturition

multicellular organismal process [inference]

tissue remodeling

developmental process [inference]

anatomical structure development [inference]

tube development [inference]

digestive tract development

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

camera-type eye development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

hepatocyte differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to nematode

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to food

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to increased oxygen levels [inference]

response to hyperoxia

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to toxic substance [inference]

response to herbicide

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to organic cyclic compound [inference]

cellular response to organic cyclic compound

response to phenylpropanoid [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to diphenyl ether

response to polycyclic arene [inference]

response to 3-methylcholanthrene

response to 2,3,7,8-tetrachlorodibenzodioxine

response to lipid [inference]

response to ether [inference]

response to diphenyl ether

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to ketone [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to inorganic substance [inference]

response to metal ion [inference]

response to iron ion [inference]

response to iron(III) ion

response to copper ion [inference]

cellular response to copper ion

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to ether [inference]

response to diphenyl ether

response to ketone [inference]

response to hydroxyisoflavone [inference]

response to genistein

response to salt [inference]

response to iron(III) ion

response to Aroclor 1254

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to copper ion

cellular response to organic substance [inference]

cellular response to organic cyclic compound

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinoic acid metabolic process [inference]

retinoic acid biosynthetic process [inference]

9-cis-retinoic acid biosynthetic process

9-cis-retinoic acid metabolic process [inference]

9-cis-retinoic acid biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrion	HTP	34800366
mitochondrial inner membrane	ISS
endoplasmic reticulum membrane	TAS
intracellular membrane-bounded organelle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

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GO Term	Evidence Code	PMID
monooxygenase activity	TAS
monooxygenase activity	IBA
iron ion binding	IEA
protein binding	IPI	25416956 25910212
arachidonic acid monooxygenase activity	IDA	15041462

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

monooxygenase activity

arachidonic acid monooxygenase activity

steroid hydroxylase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

flavonoid 3'-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

fatty acid omega-hydroxylase activity [inference]

long-chain fatty acid omega-hydroxylase activity

vitamin D 24-hydroxylase activity

oxidoreductase activity, acting on diphenols and related substances as donors

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

arachidonic acid monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

flavonoid 3'-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

fatty acid omega-hydroxylase activity [inference]

long-chain fatty acid omega-hydroxylase activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

hydroperoxy icosatetraenoate dehydratase activity

demethylase activity

binding [inference]

protein binding

enzyme binding

heat shock protein binding [inference]

protein-folding chaperone binding [inference]

Hsp70 protein binding

small molecule binding [inference]

oxygen binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome p450

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

KEGG BRITE Database

Orthology

K07408

Name

cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]

References

Rhea

RHEA:37943

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

RHEA:37947

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

H₂O + 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

12881489

RHEA:48636

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

H₂O + 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

RHEA:55556

a hydroperoxyeicosatetraenoate

an oxoeicosatetraenoate + H₂O

Enzyme

4.2.1.152

PMID

RHEA:37935

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

RHEA:17149

an organic molecule + O₂

H₂O + H⁺ + an alcohol

Enzyme

1.14.14.1

PMID

RHEA:37927

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

H₂O + 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate

Enzyme

4.2.1.152

PMID

17045234

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:4607	biliary tract cancer	Alliance of Genome Resources
DOID:5041	esophageal cancer	Alliance of Genome Resources
DOID:552	pneumonia	Alliance of Genome Resources
DOID:6132	bronchitis	Alliance of Genome Resources
DOID:6196	reactive arthritis	Alliance of Genome Resources
DOID:7147	ankylosing spondylitis	Alliance of Genome Resources
DOID:783	end stage renal disease	Alliance of Genome Resources
DOID:824	periodontitis	Alliance of Genome Resources
DOID:8552	chronic myeloid leukemia	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1543	Xenbase:XB-GENE-990173
Xenopus tropicalis	1544	Xenbase:XB-GENE-990173
Mus musculus	13076	Xenbase:XB-GENE-990173	MOUSE61937
Xenopus tropicalis	13077	Xenbase:XB-GENE-990173
Rattus norvegicus	24296	Xenbase:XB-GENE-990173	RATNO42132
Xenopus tropicalis	24297	Xenbase:XB-GENE-990173
Danio rerio	140634		DANRE14017
Bos taurus	282870		BOVIN16656
Sus scrofa	403103		PIGXX32054
Pan troglodytes	453744		PANTR10801

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements