severe pre-eclampsia

Summary
Synonym
  • Severe pre-eclampsia, with delivery
  • antepartum severe pre-eclampsia
  • postpartum severe pre-eclampsia
  • severe preeclampsia
Definition
A pre-eclampsia that has_symptom at least one of the following: SBP of 160mm HG or higher or DPB of 110mm HG or higher on 2 occasions at least 6 hours apart, proteinuria more than 5g in a 24-hour collection, pulmonary edema or cyanosis, oliguria, persistent headaches, epigastric pain and/or impaired liver function, thrombocytopenia, oligohydramnios, decreased fetal growth or placental abruption.
Super Class
pre-eclampsia
Disease Ontology
DOID:13129
UMLS
Related Genes
Displaying all 8 entries
Gene ID Gene Symbol Description Source
90 ACVR1 activin A receptor type 1
328 APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1
1284 COL4A2 collagen type IV alpha 2 chain
2878 GPX3 glutathione peroxidase 3
4012 LNPEP leucyl and cystinyl aminopeptidase
5950 RBP4 retinol binding protein 4
51752 ERAP1 endoplasmic reticulum aminopeptidase 1
64167 ERAP2 endoplasmic reticulum aminopeptidase 2
Displaying all 5 entries
Gene ID Gene Symbol Description Source
11477 Acvr1 activin A receptor, type 1
12827 Col4a2 collagen, type IV, alpha 2
19662 Rbp4 retinol binding protein 4, plasma
80898 Erap1 endoplasmic reticulum aminopeptidase 1
240028 Lnpep leucyl/cystinyl aminopeptidase
Displaying all 3 entries
Gene ID Gene Symbol Description Source
25703 Rbp4 retinol binding protein 4
79558 Acvr1 activin A receptor type 1
171105 Lnpep leucyl and cystinyl aminopeptidase
Displaying all 6 entries
Gene ID Gene Symbol Description Source
173297 F49B2.6 Aminopeptidase
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
176829 daf-1 Cell surface receptor daf-1
179763 anp-1 Aminopeptidase
181178 gpx-5 Glutathione peroxidase
182513 gpx-3 Glutathione peroxidase 3

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024