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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
major depressive disorder
Summary
- Synonym
-
- clinical depression
- major depression
- recurrent major depression
- single major depressive episode
- unipolar depression
- Definition
- A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
- Super Class
- depressive disorder
External Links
- Disease Ontology
- DOID:1470
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5321 | PLA2G4A | phospholipase A2 group IVA | |
| 5332 | PLCB4 | phospholipase C beta 4 | |
| 5335 | PLCG1 | phospholipase C gamma 1 | |
| 5507 | PPP1R3C | protein phosphatase 1 regulatory subunit 3C | |
| 5538 | PPT1 | palmitoyl-protein thioesterase 1 | |
| 5621 | PRNP | prion protein (Kanno blood group) | |
| 5660 | PSAP | prosaposin | |
| 5728 | PTEN | phosphatase and tensin homolog | |
| 5730 | PTGDS | prostaglandin D2 synthase | |
| 5742 | PTGS1 | prostaglandin-endoperoxide synthase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | |
| Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | |
| Q9NR19 | Acetyl-coenzyme A synthetase, cytoplasmic | |
| Q9NR45 | Sialic acid synthase | |
| Q9NRA2 | Sialin | |
| Q9NYP7 | Very long chain fatty acid elongase 5 | |
| Q9NZ01 | Very-long-chain enoyl-CoA reductase | |
| Q9P035 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 | |
| Q9P121 | Neurotrimin | |
| Q9P232 | Contactin-3 |
