major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 181 - 190 of 217 in total
Gene ID Gene Symbol Description Source
51548 SIRT6 sirtuin 6
51763 INPP5K inositol polyphosphate-5-phosphatase K
53942 CNTN5 contactin 5
54187 NANS N-acetylneuraminate synthase
54625 PARP14 poly(ADP-ribose) polymerase family member 14
54675 CRLS1 cardiolipin synthase 1
55830 GLT8D1 glycosyltransferase 8 domain containing 1
55902 ACSS2 acyl-CoA synthetase short chain family member 2
56994 CHPT1 choline phosphotransferase 1
57104 PNPLA2 patatin like phospholipase domain containing 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024