major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 71 - 80 of 217 in total
Gene ID Gene Symbol Description Source
3290 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1
3340 NDST1 N-deacetylase and N-sulfotransferase 1
3356 HTR2A 5-hydroxytryptamine receptor 2A
3383 ICAM1 intercellular adhesion molecule 1
3423 IDS iduronate 2-sulfatase
3425 IDUA alpha-L-iduronidase
3554 IL1R1 interleukin 1 receptor type 1
3613 IMPA2 inositol monophosphatase 2
3636 INPPL1 inositol polyphosphate phosphatase like 1
3703 STT3A STT3 oligosaccharyltransferase complex catalytic subunit A
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A
Related Glycoprotein
Displaying entry 161 - 161 of 161 in total
UniProt ID Protein Name Source
Q9Y6A2 Cholesterol 24-hydroxylase

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