chronic granulomatous disease

Summary
Synonym
  • Bridges-Good syndrome
  • CGD
  • Congenital dysphagocytosis
  • Quie syndrome
Definition
A phagocyte bactericidal dysfunction characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, liver, lymph nodes, and bones may occur along with swollen areas of inflamed tissues known as granulomas that can be widely distributed.
Super Class
phagocyte bactericidal dysfunction
External Links
Disease Ontology
DOID:3265
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
83666 PARP9 poly(ADP-ribose) polymerase family member 9
151056 PLB1 phospholipase B1
Displaying 1 entry
Gene ID Gene Symbol Description Source
43222 Tl Toll

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024