myelofibrosis

Summary
Synonym
  • Agnogenic myeloid metaplasia
  • Aleukemic myelosis
  • Megakaryocytic myelosclerosis
  • bone Marrow Fibrosis
  • myelosclerosis
  • primary myelofibrosis
Definition
A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.
Super Class
myeloid neoplasm
Disease Ontology
DOID:4971
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
9612 NCOR2 nuclear receptor corepressor 2
171023 ASXL1 ASXL transcriptional regulator 1
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
228790 Asxl1 ASXL transcriptional regulator 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
24842 Tp53 tumor protein p53
29199 Hfe homeostatic iron regulator
59086 Tgfb1 transforming growth factor, beta 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
41166 Calr Calreticulin
41737 trx trithorax
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
Displaying all 2 entries
Gene ID Gene Symbol Description Source
175182 ver-1 Protein ver-1
186632 ver-4 Tyrosine-protein kinase receptor ver-4
Displaying 1 entry
Gene ID Gene Symbol Description Source
850399 SNT1 Snt1p
The Human Phenotype Ontology
Displaying entries 11 - 20 of 35 in total
HPO ID HPO Term
HP:0001876 Pancytopenia
HP:0012378 Fatigue
HP:0001945 Fever
HP:0001433 Hepatosplenomegaly
HP:0004326 Cachexia
HP:0000967 Petechiae
HP:0001974 Leukocytosis
HP:0004377 Hematological neoplasm
HP:0001744 Splenomegaly
HP:0005561 Abnormal bone marrow cell morphology
Displaying 1 entry
Gene ID Gene Symbol Description
811 CALR calreticulin

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Last updated: December 9, 2024