acquired immunodeficiency syndrome

Summary
Synonym
  • AIDS
  • acquired Immune deficiency
Definition
A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
Super Class
human immunodeficiency virus infectious disease
Disease Ontology
DOID:635
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
7132 TNFRSF1A TNF receptor superfamily member 1A
7133 TNFRSF1B TNF receptor superfamily member 1B
9437 NCR1 natural cytotoxicity triggering receptor 1
30835 CD209 CD209 molecule
259197 NCR3 natural cytotoxicity triggering receptor 3
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
170776 Cd209c CD209c antigen
170779 Cd209d CD209d antigen
170786 Cd209a CD209a antigen
216831 Arhgap44 Rho GTPase activating protein 44
Displaying all 9 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24835 Tnf tumor necrosis factor
24930 Cd8a CD8 subunit alpha
24932 Cd4 Cd4 molecule
25625 Tnfrsf1a TNF receptor superfamily member 1A
117547 Ncr1 natural cytotoxicity triggering receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
378947 Bst2 bone marrow stromal cell antigen 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 2 entries
Gene ID Gene Symbol Description Source
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024