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progressive multifocal leukoencephalopathy
Summary
- Definition
- A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.
- Super Class
- viral infectious disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 142 | PARP1 | poly(ADP-ribose) polymerase 1 | |
| 416 | ARSF | arylsulfatase F | |
| 847 | CAT | catalase | |
| 929 | CD14 | CD14 molecule | |
| 2571 | GAD1 | glutamate decarboxylase 1 | |
| 5329 | PLAUR | plasminogen activator, urokinase receptor | |
| 5621 | PRNP | prion protein (Kanno blood group) | |
| 5660 | PSAP | prosaposin | |
| 6342 | SCP2 | sterol carrier protein 2 | |
| 6646 | SOAT1 | sterol O-acyltransferase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O60760 | Hematopoietic prostaglandin D synthase | |
| P04040 | Catalase | |
| P04156 | Major prion protein | |
| P07602 | Prosaposin | |
| P08571 | Monocyte differentiation antigen CD14 | |
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P35610 | Sterol O-acyltransferase 1 | |
| P54793 | Arylsulfatase F | |
| Q03405 | Urokinase plasminogen activator surface receptor |
