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amyloidosis
Summary
- Synonym
-
- amyloid disease
- Definition
- A disease of metabolsism that is characterized by extracellular tissue deposition of mis-folded amyloid fibrils built up by twisted protofilaments, deposited in the spaces between the cells of vital organs, causing disruption of organ tissue structure and function. These deposits may result in a wide range of clinical manifestations depending upon their type, location, and the amount of deposition.
- Super Class
- disease of metabolism
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7124 | TNF | tumor necrosis factor | |
| 7412 | VCAM1 | vascular cell adhesion molecule 1 | |
| 7941 | PLA2G7 | phospholipase A2 group VII | |
| 8540 | AGPS | alkylglycerone phosphate synthase | |
| 8560 | DEGS1 | delta 4-desaturase, sphingolipid 1 | |
| 8803 | SUCLA2 | succinate-CoA ligase ADP-forming subunit beta | |
| 9370 | ADIPOQ | adiponectin, C1Q and collagen domain containing | |
| 9993 | DGCR2 | DiGeorge syndrome critical region gene 2 | |
| 10457 | GPNMB | glycoprotein nmb | |
| 10858 | CYP46A1 | cytochrome P450 family 46 subfamily A member 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P15289 | Arylsulfatase A | |
| P16112 | Aggrecan core protein | |
| P16444 | Dipeptidase 1 | |
| P18054 | Polyunsaturated fatty acid lipoxygenase ALOX12 | |
| P18827 | Syndecan-1 | |
| P19320 | Vascular cell adhesion protein 1 | |
| P20138 | Myeloid cell surface antigen CD33 | |
| P20916 | Myelin-associated glycoprotein | |
| P22303 | Acetylcholinesterase | |
| P23219 | Prostaglandin G/H synthase 1 |
