achalasia

Summary
Synonym
  • Lack of reflex relaxation of lower oesophageal sphincter
  • achalasia of cardia
  • achalasia of esophagus
  • cardiospasm
  • esophageal achalasia
  • hypertensive lower esophageal sphincter
Definition
An esophageal disease that is characterized by an inability of the esophagus to move food toward the stomach resulting from the lower esophogeal sphincter not fully relaxing during swallowing.
Super Class
esophageal disease
Disease Ontology
DOID:9164
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 4 entries
Gene ID Gene Symbol Description Source
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
7433 VIPR1 vasoactive intestinal peptide receptor 1
8086 AAAS aladin WD repeat nucleoporin
Displaying all 2 entries
Gene ID Gene Symbol Description Source
16905 Lmna lamin A
24064 Spry2 sprouty RTK signaling antagonist 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025