GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol	Gene ID
DOID:5844	myocardial infarction	ACE ALDH2 ANXA5 CAT CD14 CHI3L1 CS CTS2 CYP11B1 CYP1B1 CYP2J2 CYP2R1 DAG1 DCN Dg FOL2 FZO1 G6PD GCH1 GPX1 Gch1 Gch1 HADH HDAC4 HSD11B2 ICAM1 Idgf1 Idgf2 Idgf3 Idgf4 LCAT LGALS2 LIPG LPL Lcat Lcat Lipg Lipg Lpl Lpl MDH1 MDH2 MDH2 MFN2 MGM1 Marf Mfn2 NCAM1 NEIL3 NLRP3 Nlrp3 Nlrp3 OLR1 OPA1 Opa1 Opa1 PDE2 PDE5A PLA2G7 PLAUR PLC1 PLCB1 PLCB3 PON1 PTGIS PTGS2 Pde11 Pde5a Pde5a Pde6 Pla2g7 Plc21C Plcb1 Plcb1 Plcb3 Pon1 Pon1 Pu RAD50 RAD50 REG1B Rad50 Rrp1 SDC1 SDC4 SELP Sdc VCAN cat-4 cht-1 daf-2 fzo-1 opa1 paf-2 rad-50 rad50	10111 1116 114548 120227 1431 14528 1462 1545 1573 1584 1605 1634 1636 16816 16891 16956 170731 171115 171116 173990 175410 179472 179678 180628 180704 18795 18797 18979 216799 217 23236 242202 24530 24539 24654 2539 2643 27226 287362 2876 291437 29244 3033 308 31581 31926 3291 33204 33500 3383 34978 34979 34981 35107 36773 37415 37447 37564 3931 3957 4023 41760 4191 4684 492332 4973 4976 5329 5331 5444 55247 5740 5743 5968 6382 6385 64012 6403 74143 7941 84024 847 851977 852477 853183 853777 853994 854386 854542 855471 855860 8654 929 9388 9759 9927
DOID:1574	alcohol use disorder	ACSS2 ADH5 ALDH2 ARF6 Arf6 Arf6 COMT CYP2E1 FADS1 FADS2 GAD1 GAD2 HDAC1 HDAC2 Hdac2 N NCAM1 PIK3CB PIK3CD PPP1R3B PPP1R3C PSPH Psph Psph RAC1 RAC3 RPD3 Rac1 Rac1 Rac3 SER2 SHMT1 SHMT2 ST6GAL1 SiaT St6gal1 St6gal1 aay hda-1 st6gal1.L st6gal1.S st6gal1 st6gal1	100491268 100678 108717116 108718183 11845 128 1312 15182 1571 170758 179959 19353 20440 217 25197 2571 2572 304429 3066 31293 363875 37950 382 38565 39085 3992 445376 4684 5291 5293 5507 55902 5723 5879 5881 6470 6472 6480 79121 79660 853122 855386 9415
DOID:0110657	congenital myasthenic syndrome 8	AGRN	375790
DOID:9245	Alagille syndrome	N	31293
DOID:0050816	urofacial syndrome	HPSE2	60495
DOID:2754	glycogen storage disease VI	GPH1 Glyp PYGL Pygl Pygl	110095 33386 5836 64035 856289
DOID:0110292	autosomal recessive limb-girdle muscular dystrophy type 2O	KL POMGNT1 Pomgnt1 Pomgnt1 pomgnt1.L pomgnt1.S pomgnt1 pomgnt1	100158594 362567 414570 495292 55624 571876 68273 9365
DOID:11934	head and neck cancer	CYP1A1 GPX3 HPSE SOAT1	10855 1543 2878 6646
DOID:0110379	retinitis pigmentosa 43	PDE6A	5145
DOID:0111240	congenital muscular dystrophy-dystroglycanopathy type A2	PMT2 PMT3 PMT6 POMT2 Pomt2 Pomt2 pomt2.L pomt2 pomt2 tw	100490100 108698684 217734 29954 31024 563878 688673 851210 853113 854499