GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID ▼	Disease Name	Gene Symbol	Gene ID
DOID:1686	glaucoma	EEF2 EFT1 Eef2 Eef2 HDAC1 HDAC1 Hdac1 Hdac1 PTEN PTGS1 RPD3 eEF2 eef2.1.L eef2b hda-1 hdac1.L	13629 179959 1938 29565 297893 3065 326929 35422 380348 38565 397868 433759 5728 5742 851993 855386
DOID:1682	congenital heart disease	GPX3 HDAC3 N PLCB2 Plc21C Plcb2 Plcb2	18796 2878 31293 33204 5330 85240 8841
DOID:1679	cystitis	CAT PTGS2	5743 847
DOID:1631	benign breast phyllodes tumor	INPP4B PTEN	5728 8821
DOID:162	cancer	AADAC ABCC1 ABO ACADS ACSM3 ACSS2 ACTB AICDA ALDH1A3 ALOX15 APRT ARF1 CALR CD44 CD74 CDA CDH13 CDIPT CDS1 CDS1 CDS2 CEACAM5 CG1598 CHPT1 CRYBG1 CYB5R2 CYP19A1 CYP1A1 CYP1B1 CYP24A1 DAG1 DGKI DHDDS DNM1L DNM3 DOG2 DUT1 DUT Dut Dut EXT1 EXTL1 FHIT G6PD GAD1 GALC GCNT2 GET3 GET3 GLB1 GLDC GLS GNPNAT1 GPX3 Get3 Get3 HACD1 HACD2 HDAC1 HDAC2 HDAC3 HDAC9 HEXA HK2 HPGDS HRAS HSP90AA1 Hras Hras Hsp90aa1 Hsp90aa1 ICAM1 IDH1 IDH2 KL KRAS Kras Kras LGALS3 LGALS4 LRRK2 LYPLA1 Lrrk2 MEST MMUT MRC1 MSLN N NRAS NSDHL Nras OPCML PCM1 PFKFB2 PGK1 PGK1 PGK2 PGM3 PIG-Z PIGZ PIK3CA PIK3CB PIK3CD PIK3CG PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PKM PLAAT4 PLCD1 PLCG1 POL2 POLE PRPS1 PRSS21 PTEN PTGS2 Pgm3 Pigz Pigz PolE1 Pole RAB5A RAB5B RAB5C RAC1 RAS1 RAS2 RECK RFT1 RFT1 RIOK1 RPE65 RRAS Rab5a Rab5a Rab5al1 Rab5b Rab5c Ras85D SAMHD1 SDC2 SDHC SHMT1 SHMT2 SMP3 SOAT1 SQLE STS SULF1 SULT1E1 TEP1 TNFRSF10C TPI1 TPI1 TUSC3 UGP2 UNG UPP1 asna-1 get3 get3	100361891 10059 1012 10232 1040 10423 10434 1048 10942 109785 110074 120892 13 1543 1545 15461 15519 1588 1591 1605 16653 176254 1854 18973 19344 19345 19835548 201562 202 2131 2134 220 2272 23213 23396 239827 24525 246 24605 2539 2571 2581 25939 26052 2651 271457 2720 27306 2731 2744 28 2878 288919 293621 299331 303872 3065 3066 3073 3099 31293 325704 3265 3320 3383 3417 3418 35 353 35690 375 3845 3958 3960 41140 412 4232 42758 4360 4363 439 4594 4893 497778 4978 50814 51700 5208 5230 5232 5238 5290 5291 5293 5294 5305 5315 5333 5335 5426 55902 5631 56495 56994 5728 57379 5743 5868 5869 5878 5879 5920 60 6121 6237 6296 6383 6391 64633 6470 6472 64841 6646 66725 6713 6783 7167 7360 7374 7378 779794 79837 7991 79947 80235 811 83732 8394 8395 8396 8434 850370 851458 851620 852261 852317 852554 854268 854320 855459 855595 855625 856439 856652 8760 8794 8841 9162 91869 9200 9365 960 972 9734 978
DOID:1612	breast cancer	AADAC ACACA ACE ACSL3 AKR1A1 AKR1B10 ALDH1A3 ALOX12 ANXA7 ATG26 Alox12 BST2 CACNA2D3 CALR CBR1 CD55 CDH13 CHI3L1 CHKA COMT CTS2 CYB5R3 CYP17A1 CYP19A1 CYP1A1 CYP1A2 CYP1B1 CYP2C19 CYP3A4 CYP7B1 DPM1 DPP1 EEF1A1 EIF2S3 FASN FHIT GPX1 GPX3 HDAC1 HK2 HMMR HPGDS HPSE HRAS HS3ST2 HYAL2 ICAM1 INPP4B INSR Idgf1 Idgf2 Idgf3 Idgf4 KL KRAS Kras Kras MBD4 MCAT NEU1 NT5E OGDHL OGG1 OGG1 Ogg1 Ogg1 Ogg1 PARP1 PEMT PIK3CA PIK3CB PIK3CD PIK3CG PKM PLA2R1 PLC1 PLCD1 PLCG1 PLPP4 PON1 PTEN PTGES3 PTGS1 PTGS2 Plcg1 Plcg1 Plpp4 Pon1 Pon1 RAC1 RAD50 RAD50 RECK RERG RHO1 RHO2 RHOA Rac1 Rac1 Rad50 Ras85D Rerg Rhoa Rhoa Rrp1 SHMT1 SNF1 STS SULT1E1 TEP1 TNFRSF10C TUB3 UGCG UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 YTA7 cht-1 daf-2 plc-3 rad-50 rad50 ugt-61 ugt1a1 ugt1a6 ugt1a7 ugt1ab	100135191 100384891 100489505 10111 1012 10327 10400 10728 10855 1116 1119 11684 117273 11848 13 1312 142 1543 1544 1545 1557 1576 1586 1588 1604 1636 16653 1727 174586 175410 179678 180628 18294 185500 18803 18979 1915 19353 196051 1968 2181 2194 220 2272 22925 232441 239 24525 24861 25738 27306 27349 2876 2878 3065 3099 31 310 3161 31806 31926 3265 33500 3383 34978 34979 34981 35105 35137 35138 35139 363875 3643 37564 381925 3845 387 394436 40079 406731 41140 412 41334 41574 42538 4758 4907 4968 5290 5291 5293 5294 5315 5333 5335 53501 53502 53503 53506 53507 53511 53512 53583 5444 54658 55753 55799 57016 5728 5742 5743 5879 64012 6470 6783 684 7357 811 81528 84024 8434 85004 850886 851878 851977 852088 853186 854768 854915 854942 855471 855595 855634 855860 856294 856313 8692 8794 8821 8930 9365 9420 9956
DOID:161	keratosis	CAT	847
DOID:1596	depressive disorder	ABAT ACE CAT CHAT COMT CYP1A2 CYP2B6 CYP2E1 CYP3A5 FZO1 GPX1 GPX3 HDAC5 L1CAM MFN2 Marf Mfn2 NCAM1 PDE4D PLA2G2A Pde4d Pde4d Pla2g2a Pla2g2a dnc fzo-1 hda-4 pde-4	10014 1103 1312 1544 1555 1571 1577 1636 170731 173990 174235 18 181723 18780 238871 24627 2876 2878 29692 31309 31581 3897 4684 5144 5320 847 852477 9927
DOID:1595	melancholic depression	ACE COMT morc-1	1312 1636 175711
DOID:1591	renovascular hypertension	ACE G6PD HDAC8 HOS1 Hdac8 Hdac8 PTGS1 hdac8 hdac8	100145561 1636 2539 363481 406740 55869 5742 70315 856181