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transketolase

Summary

Gene Symbol

TKT

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100174016
KEGG Gene ID: pon:100174016
PubChem: 100174016

Annotation

Keyword

Acetylation
Calcium
Isopeptide bond
Magnesium
Metal-binding
Phosphoprotein
Reference proteome
Thiamine pyrophosphate
Transferase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R4C1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
pentose-phosphate shunt, non-oxidative branch	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

generation of precursor metabolites and energy [inference]

pentose-phosphate shunt, non-oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

generation of precursor metabolites and energy [inference]

pentose-phosphate shunt, non-oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
extracellular exosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
thiamine pyrophosphate binding	IEA	30032202
transketolase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transketolase or transaldolase activity [inference]

transketolase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00615

Name

transketolase [EC:2.2.1.1]

References

8419340

Rhea

D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate

D-xylulose 5-phosphate + aldehydo-D-ribose 5-phosphate

Enzyme

2.2.1.1

PMID

D-erythrose 4-phosphate + D-xylulose 5-phosphate

β-D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate

Enzyme

2.2.1.1

Ortholog

Displaying entries **21 - 30** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100396350		CALJA12922
Cercocebus atys	105585582		CERAT02038
Macaca fascicularis	102136564		MACFA27354
Macaca mulatta	694327		MACMU28475
Macaca nemestrina	105480569		MACNE07229
Papio anubis	101003112		PAPAN24763
Mandrillus leucophaeus	105543982		MANLE17356
Pan paniscus	100976799		PANPA28072
Pan troglodytes	460443		PANTR31353
Homo sapiens	7086		HUMAN70575

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024