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prostaglandin I2 synthase

Summary

Gene Symbol

PTGIS

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100440673
KEGG Gene ID: pon:100440673
PubChem: 100440673

Annotation

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
prostaglandin biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process [inference]

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

prostanoid metabolic process [inference]

prostaglandin metabolic process [inference]

prostaglandin biosynthetic process

prostanoid biosynthetic process [inference]

prostaglandin biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	22301074
prostaglandin-I synthase activity	IEA	22301074 30032202
monooxygenase activity	IEA	22301074
iron ion binding	IEA	22301074
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

prostaglandin-I synthase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01831

Name

prostacyclin synthase [EC:5.3.99.4]

References

Ortholog

Displaying entries **21 - 30** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cercocebus atys	105585406		CERAT24900
Macaca fascicularis	102123511		MACFA01919
Macaca mulatta	703407		MACMU01137
Macaca nemestrina	105470700		MACNE19778
Papio anubis	101015498		PAPAN11932
Mandrillus leucophaeus	105548960		MANLE29720
Pan paniscus	100987973		PANPA22532
Pan troglodytes	458323		PANTR25103
Homo sapiens	5740		HUMAN57457
Ursus americanus	123775935		URSAM09534

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Last updated: August 19, 2024