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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase with thrombospondin type 1 motif 5
Summary
- Gene Symbol
-
- adamts5
- Organism
- Xenopus tropicalis (tropical clawed frog)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A6I8R102 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| collagen-containing extracellular matrix | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metal ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- I: Lipid transport and metabolism
- K: Transcription
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12800 | mucopolysaccharidosis VI | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:8398 | osteoarthritis | |
| DOID:90 | degenerative disc disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11096 | 9606_0:001a58 | HGNC:221 | ||
| 23794 | MGI:1346321 | |||
| 286805 | 9913_0:000162 | |||
| 304135 | RGD:735196 | |||
| 427971 | 9031_0:000824 | |||
| 487713 | 9615_0:0049ad | |||
| 707672 | 9544_0:0010d5 | |||
| 100008799 | 9986_0:002abf | |||
| 100021415 | 13616_0:002d51 | |||
| 100066005 | 9796_0:00490e |
