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Standards Ontologies Notations
cytochrome P450 family 17 subfamily A member 1

Summary
Gene Symbol
  • CYP17A1
Organism
Saimiri boliviensis (Bolivian squirrel monkey)
NCBI Gene
101048584
KEGG Gene ID
sbq:101048584
PubChem
101048584
Annotation
Keyword
  • Heme
  • Lipid metabolism
  • Monooxygenase
  • Reference proteome
  • Signal
  • Steroidogenesis
Proteins
Displaying 1 entry
UniProt Protein Name
A0A2K6SIN1
  • CYPXVII
  • Cytochrome P450 17A1
  • Cytochrome P450-C17
  • Steroid 17-alpha-monooxygenase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
hormone biosynthetic process
progesterone metabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K00512
Name
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
References
Rhea

RHEA:50236

O2 + pregnenolone
H2O + H+ + 17α-hydroxypregnenolone
Enzyme
PMID

RHEA:50244

O2 + 17α-hydroxypregnenolone
H2O + H+ + 3β-hydroxyandrost-5-en-17-one + acetate
Enzyme
PMID

RHEA:65760

O2 + a C21-steroid
a 17α-hydroxy-C21-steroid + H2O + H+
Enzyme
PMID

RHEA:14753

O2 + 17α-hydroxyprogesterone
H2O + H+ + androst-4-ene-3,17-dione + acetate
Enzyme
PMID

RHEA:46308

O2 + progesterone
H2O + H+ + 17α-hydroxyprogesterone
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 88 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
1586 HUMAN02789
13074 MOUSE26570
25146 RATNO17926
281739 BOVIN21442
399692 DANRE05649
403330 PIGXX08420
450141 PANTR01466
477807 CANLF11436
493967 FELCA26692
493968 SHEEP11572
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024