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cytochrome P450 family 17 subfamily A member 1

Summary

Gene Symbol

CYP17A1

Aliases

CPT7
P450C17
S17AH
Steroid 17-alpha-monooxygenase

Organism

Homo sapiens (human)

External Links

NCBI Gene

1586

HGNC

2593

KEGG Gene ID

hsa:1586

PubChem

1586

Alliance of Genome Resources

HGNC:2593

Annotation

Keyword

3D-structure
Congenital adrenal hyperplasia
Disease variant
Heme
Lipid metabolism
Lyase
Membrane
Microsome
Monooxygenase
Phosphoprotein
Reference proteome
Signal
Steroidogenesis

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q1HB44	CYPXVII Cytochrome P450 17A1 Cytochrome P450-C17 Steroid 17-alpha-monooxygenase
P05093	17-alpha-hydroxyprogesterone aldolase CYPXVII Cytochrome P450 17A1 Cytochrome P450-C17 Steroid 17-alpha-monooxygenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
hormone biosynthetic process	IBA IDA	22266943
sex differentiation		9326943
androgen biosynthetic process
glucocorticoid biosynthetic process	IEA TAS
progesterone metabolic process	IBA IDA	22266943

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process

androgen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

androgen metabolic process [inference]

androgen biosynthetic process

hormone biosynthetic process

androgen biosynthetic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

androgen metabolic process [inference]

androgen biosynthetic process

glucocorticoid metabolic process [inference]

glucocorticoid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

androgen metabolic process [inference]

androgen biosynthetic process

glucocorticoid metabolic process [inference]

glucocorticoid biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

olefinic compound metabolic process [inference]

progesterone metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

androgen metabolic process [inference]

androgen biosynthetic process

glucocorticoid metabolic process [inference]

glucocorticoid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

steroid hormone biosynthetic process [inference]

cellular process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

progesterone metabolic process

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

progesterone metabolic process

androgen metabolic process [inference]

androgen biosynthetic process

hormone biosynthetic process

androgen biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum		9326943
axon	IEA
neuronal cell body	IEA
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

cell body [inference]

neuronal cell body

Displaying **all 5** entries
GO Term	Evidence Code	PMID
steroid 17-alpha-monooxygenase activity	IBA IDA IMP TAS	22170710 22266943 24140098 36640554
oxygen binding		2808364
iron ion binding	IEA
17-alpha-hydroxyprogesterone aldolase activity	IBA IMP	24140098
heme binding	IDA	22266943