osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
650 BMP2 bone morphogenetic protein 2
796 CALCA calcitonin related polypeptide alpha
799 CALCR calcitonin receptor
1277 COL1A1 collagen type I alpha 1 chain
1278 COL1A2 collagen type I alpha 2 chain
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
1588 CYP19A1 cytochrome P450 family 19 subfamily A member 1
2099 ESR1 estrogen receptor 1
3480 IGF1R insulin like growth factor 1 receptor
3552 IL1A interleukin 1 alpha
Displaying all 4 entries
Gene ID Gene Symbol Description Source
15979 Ifngr1 interferon gamma receptor 1
18383 Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
21943 Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11
102866 Pls3 plastin 3 (T-isoform)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24310 Ace angiotensin I converting enzyme
24483 Igf2 insulin-like growth factor 2
24577 Myc MYC proto-oncogene, bHLH transcription factor
25608 Lep leptin
84023 Ptger4 prostaglandin E receptor 4

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025