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estrogen receptor 1

Summary

Gene Symbol

ESR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2099

PubChem

2099

Alliance of Genome Resources

HGNC:3467

Annotation

Keyword

3D-structure
Activator
Alternative promoter usage
Alternative splicing
Cell membrane
Cytoplasm
DNA-binding
Direct protein sequencing
Disease variant
Glycoprotein
Golgi apparatus
Methylation
Nucleus
Osteoporosis
Palmitate
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Steroid-binding
Transcription regulation
Transmembrane
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 6** entries
UniProt	Protein Name
G4XH65	ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1
A0A125SXW3	ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1
P03372	ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1
Q9UBT1
A8KAF4	ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1
H0Y4W6	ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 47 in total

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GO Term	Evidence Code	PMID
positive regulation of fibroblast proliferation	IEA
prostate epithelial cord elongation	IEA
cellular response to estrogen stimulus	IBA
epithelial cell development	IEA
positive regulation of DNA-binding transcription factor activity	IDA	10681512 9328340

GO Hierarchy

biological process

metabolic process [inference]

hormone metabolic process [inference]

androgen metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

androgen metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

androgen metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

androgen metabolic process

cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway

intracellular steroid hormone receptor signaling pathway

intracellular estrogen receptor signaling pathway

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway

intracellular estrogen receptor signaling pathway

cell population proliferation [inference]

fibroblast proliferation

epithelial cell proliferation [inference]

mammary gland epithelial cell proliferation [inference]

epithelial cell proliferation involved in mammary gland duct elongation

cellular developmental process [inference]

cell differentiation [inference]

stem cell differentiation

cell development [inference]

epithelial cell development

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

transcription preinitiation complex assembly [inference]

RNA polymerase II preinitiation complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

transcription preinitiation complex assembly [inference]

RNA polymerase II preinitiation complex assembly

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

protein-DNA complex assembly [inference]

transcription preinitiation complex assembly [inference]

RNA polymerase II preinitiation complex assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

antral ovarian follicle growth

reproductive structure development [inference]

gonad development [inference]

male gonad development

genitalia development [inference]

female genitalia development [inference]

vagina development

uterus development

prostate gland growth [inference]

prostate gland morphogenetic growth [inference]

prostate epithelial cord elongation

prostate gland epithelium morphogenesis [inference]

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

prostate epithelial cord elongation

mammary gland branching involved in pregnancy

ovulation cycle process [inference]

antral ovarian follicle growth

multicellular organismal reproductive process [inference]

maternal process involved in female pregnancy [inference]

mammary gland branching involved in pregnancy

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis [inference]

mammary gland branching involved in pregnancy

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

organ growth [inference]

prostate gland growth [inference]

prostate gland morphogenetic growth [inference]

prostate epithelial cord elongation

developmental process [inference]

developmental process involved in reproduction [inference]

antral ovarian follicle growth

reproductive structure development [inference]

gonad development [inference]

male gonad development

genitalia development [inference]

female genitalia development [inference]

vagina development

uterus development

prostate gland growth [inference]

prostate gland morphogenetic growth [inference]

prostate epithelial cord elongation

prostate gland epithelium morphogenesis [inference]

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

prostate epithelial cord elongation

mammary gland branching involved in pregnancy

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis [inference]

mammary gland branching involved in pregnancy

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis [inference]

mammary gland branching involved in pregnancy

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

prostate gland epithelium morphogenesis [inference]

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

prostate epithelial cord elongation

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis [inference]

mammary gland branching involved in pregnancy

branching involved in prostate gland morphogenesis [inference]

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development

animal organ development [inference]

gonad development [inference]

male gonad development

genitalia development [inference]

female genitalia development [inference]

vagina development

uterus development

reproductive structure development [inference]

gonad development [inference]

male gonad development

genitalia development [inference]

female genitalia development [inference]

vagina development

uterus development

mammary gland alveolus development

cellular developmental process [inference]

cell differentiation [inference]

stem cell differentiation

cell development [inference]

epithelial cell development

growth [inference]

developmental growth [inference]

antral ovarian follicle growth

organ growth [inference]

prostate gland growth [inference]

prostate gland morphogenetic growth [inference]

prostate epithelial cord elongation

developmental growth involved in morphogenesis [inference]

axis elongation [inference]

branch elongation of an epithelium [inference]

prostate epithelial cord elongation

prostate gland morphogenetic growth [inference]

prostate epithelial cord elongation

rhythmic process [inference]

ovulation cycle process [inference]

antral ovarian follicle growth

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

response to estrogen

cellular response to estrogen stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

response to estrogen

cellular response to estrogen stimulus

response to organic cyclic compound [inference]

response to estradiol

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

response to lipid [inference]

response to estradiol

cellular response to estradiol stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

response to oxygen-containing compound [inference]

response to estradiol

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to estrogen stimulus

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to estradiol stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of miRNA metabolic process [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of miRNA metabolic process [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of miRNA metabolic process [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of miRNA metabolic process [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of inflammatory response

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in prostate gland morphogenesis

regulation of morphogenesis of an epithelium [inference]

regulation of branching involved in prostate gland morphogenesis

regulation of cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway

intracellular steroid hormone receptor signaling pathway

intracellular estrogen receptor signaling pathway

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway

intracellular estrogen receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of miRNA metabolic process [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

regulation of ncRNA transcription [inference]

regulation of miRNA transcription [inference]

negative regulation of miRNA transcription

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

regulation of smooth muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

regulation of epithelial cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitric oxide biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of miRNA metabolic process [inference]

negative regulation of miRNA transcription

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

regulation of multicellular organismal process [inference]

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in prostate gland morphogenesis

regulation of reproductive process [inference]

regulation of branching involved in prostate gland morphogenesis

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of hormone levels [inference]

hormone metabolic process [inference]

androgen metabolic process

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of DNA-binding transcription factor activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of oxidoreductase activity [inference]

positive regulation of monooxygenase activity [inference]

positive regulation of nitric-oxide synthase activity

positive regulation of DNA-binding transcription factor activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of oxidoreductase activity [inference]

positive regulation of monooxygenase activity [inference]

positive regulation of nitric-oxide synthase activity

regulation of oxidoreductase activity [inference]

regulation of monooxygenase activity [inference]

positive regulation of monooxygenase activity [inference]

positive regulation of nitric-oxide synthase activity

regulation of nitric-oxide synthase activity [inference]

positive regulation of nitric-oxide synthase activity

positive regulation of oxidoreductase activity [inference]

positive regulation of monooxygenase activity [inference]

positive regulation of nitric-oxide synthase activity

regulation of DNA-binding transcription factor activity [inference]

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GO Term	Evidence Code	PMID
membrane	NAS	11960618
Golgi apparatus	IEA
euchromatin	IDA	17505058
protein-containing complex	IDA IMP	11595744 20080953
plasma membrane	IDA IMP TAS	15569929 16645038 22031296

GO Hierarchy

cellular component

protein-containing complex

transcription regulator complex

protein-DNA complex [inference]

chromatin

euchromatin

cellular anatomical entity [inference]

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10359819 10816575 10866662 11032808 11178989 11265755 11279242 11353774 11477071 11581164 11682626 11875103 12039952 12093804 12612073 12660241 12904255 12917342 14764652 14963108 1517211 15199063 15569929 15674350 15891768 15941852 16282588 16603732 16606617 16709599 16772533 16957778 17006958 17043237 17085477 17274640 17284441 17347654 17363140 17505058 17545996 17627277 17914104 17921256 17932106 17975005 17998543 18025262 18312651 18563714 19022902 19039327 19350539 19423554 19755138 20035625 20074560 20080953 20413580 20935677 21104395 21164480 21182203 21182205 21217774 21602804 21629692 21841772 22081016 22093364 22396492 23065768 23178685 23576398 24498420 25219498 25640309 25675114 26153859 27125460 28068668 28106301 31527615 32814053 7641693 7651415 9328340 9627117 9628876 9653119
zinc ion binding	IEA
transcription corepressor binding	IPI	12535528
TFIIB-class transcription factor binding	IPI	9841876
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	12047722 15345745

GO Hierarchy

molecular function

binding [inference]

protein binding

basal transcription machinery binding [inference]

basal RNA polymerase II transcription machinery binding [inference]

RNA polymerase II general transcription initiation factor binding [inference]

TFIIB-class transcription factor binding

transcription factor binding [inference]

transcription coregulator binding

general transcription initiation factor binding [inference]

RNA polymerase II general transcription initiation factor binding [inference]

TFIIB-class transcription factor binding

TBP-class protein binding

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear estrogen receptor binding

enzyme binding

kinase binding [inference]

protein kinase binding

ATPase binding

lipid binding [inference]

steroid binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

chromatin binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

estrogen response element binding

steroid binding

molecular transducer activity [inference]

signaling receptor activity [inference]

nuclear steroid receptor activity [inference]

nuclear estrogen receptor activity

G protein-coupled estrogen receptor activity

nuclear receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled estrogen receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nitric-oxide synthase regulator activity

transcription regulator activity [inference]

DNA-binding transcription factor activity

DNA-binding transcription factor activity, RNA polymerase II-specific

DNA-binding transcription activator activity [inference]

DNA-binding transcription activator activity, RNA polymerase II-specific

ligand-activated transcription factor activity [inference]

nuclear receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Estrogen receptor

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
estrogen response element binding
metal ion binding
nuclear steroid receptor activity
sequence-specific DNA binding
steroid binding
steroid hormone mediated signaling pathway
zinc ion binding

Displaying **all 6** entries
InterPro
Estrogen receptor/oestrogen-related receptor
Nuclear hormone receptor, ligand-binding domain
Nuclear hormone receptor-like domain superfamily
Nuclear hormone receptor
Zinc finger, NHR/GATA-type
Zinc finger, nuclear hormone receptor-type

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:10247	pleurisy	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:11132	prostatic hypertrophy	Alliance of Genome Resources
DOID:11383	cryptorchidism	Alliance of Genome Resources
DOID:11476	osteoporosis	Alliance of Genome Resources
DOID:12306	vitiligo	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	13982		MGI:1352467	MOUSE01427
Rattus norvegicus	24890		RGD:2581	RATNO18483
Danio rerio	259252		ZFIN:ZDB-GENE-020806-5
Xenopus tropicalis	394461		Xenbase:XB-GENE-482193
Sus scrofa	397435			PIGXX13216
Xenopus laevis	398733		Xenbase:XB-GENE-6255445
Xenopus laevis	398734		Xenbase:XB-GENE-864840
Canis lupus familiaris	403640			CANLF00216
Bos taurus	407238			BOVIN35994
Pan troglodytes	463079	9598_0:001b86

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements