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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Insulin-like growth factor 1 receptor
Summary
- UniProt ID
- P08069
- Gene Symbol
-
- IGF1R
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P08069
- PubChem
- P08069
- The Human Metabolome Database
- HMDBP01188
- RaftProt
- P08069
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Isopeptide bond
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| alphav-beta3 integrin-IGF-1-IGF1R complex |
| plasma membrane |
| insulin receptor complex |
| membrane |
| axon |
| intracellular membrane-bounded organelle |
| protein kinase complex |
| neuronal cell body |
| receptor complex |
| T-tubule |
Sequence
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 51 | N-linked (GlcNAc...) asparagine |
|
||
| 102 | N-linked (GlcNAc...) asparagine |
|
||
| 135 | N-linked (GlcNAc...) asparagine |
|
||
| 244 | N-linked (GlcNAc...) asparagine | |||
| 314 | N-linked (GlcNAc...) asparagine |
|
||
| 417 | N-linked (GlcNAc...) asparagine |
|
||
| 438 | N-linked (GlcNAc...) asparagine |
|
||
| 534 | N-linked (GlcNAc...) asparagine |
|
||
| 607 | N-linked (GlcNAc...) asparagine | |||
| 622 | N-linked (GlcNAc...) asparagine |
G80920RR
G11101UV
G26436YP
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Extra-nuclear estrogen signaling | Homo sapiens |
| IRS-related events triggered by IGF1R | Homo sapiens |
| Respiratory syncytial virus (RSV) attachment and entry | Homo sapiens |
| SHC-related events triggered by IGF1R | Homo sapiens |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
