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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
angiotensin I converting enzyme
Summary
- Gene Symbol
-
- Ace
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative promoter usage
- Calmodulin-binding
- Carboxypeptidase
- Cell membrane
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P47820 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of vasoconstriction | ||
| bradykinin catabolic process | ||
| proteolysis | ||
| hormone catabolic process | ||
| negative regulation of gap junction assembly |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| sperm midpiece | ||
| membrane | ||
| plasma membrane | ||
| endosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| zinc ion binding | ||
| mitogen-activated protein kinase kinase binding | ||
| calmodulin binding | ||
| peptidyl-dipeptidase activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- angiotensin-converting enzyme
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
| InterPro |
|---|
| Peptidase M2, peptidyl-dipeptidase A |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050152 | aspiration pneumonia | |
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0050851 | glomerulosclerosis | |
| DOID:0050855 | renal fibrosis | |
| DOID:0050864 | non-arteritic anterior ischemic optic neuropathy | |
| DOID:0060071 | pre-malignant neoplasm | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0080599 | Coronavirus infectious disease | |
| DOID:0080600 | COVID-19 | |
| DOID:0110861 | autosomal recessive polycystic kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1636 | HGNC:2707 | HUMAN35514 | ||
| 11421 | 10090_1:003938 | MGI:87874 | MOUSE05963 | |
| 34189 | FB:FBgn0016122 | |||
| 34805 | FB:FBgn0012037 | |||
| 180780 | WB:WBGene00000039 | |||
| 509484 | BOVIN13613 | |||
| 565980 | ZFIN:ZDB-GENE-030131-1826 | DANRE04066 | ||
| 610668 | CANLF18543 | |||
| 100009274 | RABIT07860 | |||
| 100144634 | Xenbase:XB-GENE-479789 |
