nephrotic syndrome

Summary
Definition
A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Super Class
nephrosis
Disease Ontology
DOID:1184
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 4 entries
Gene ID Gene Symbol Description Source
213 ALB albumin
2056 EPO erythropoietin
3557 IL1RN interleukin 1 receptor antagonist
51196 PLCE1 phospholipase C epsilon 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
14107 Fat1 FAT atypical cadherin 1
54631 Nphs1 nephrosis 1, nephrin
Displaying all 4 entries
Gene ID Gene Symbol Description Source
24310 Ace angiotensin I converting enzyme
24767 Scnn1b sodium channel epithelial 1 subunit beta
25122 Scnn1a sodium channel epithelial 1 subunit alpha
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
31292 kirre kin of irre
Displaying all 2 entries
Gene ID Gene Symbol Description Source
180555 syg-1 Ig-like domain-containing protein;Synaptogenesis protein syg-1
181561 syg-2 Nephrin;Synaptogenesis protein syg-2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025