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Prostaglandin G/H synthase 2
Summary
- UniProt ID
- P35355
- Gene Symbol
-
- Cox-2
- Cox2
- Ptgs2
- Gene ID
- 29527
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Dioxygenase
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Heme
- Membrane
- Microsome
- Nucleus
- Peroxidase
- Prostaglandin biosynthesis
- Reference proteome
- S-nitrosylation
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| protein-containing complex |
| neuron projection |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| nuclear inner membrane |
| nuclear outer membrane |
| caveola |
Sequence
MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKTDQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNVKGCPFASFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Biosynthesis of DHA-derived SPMs | Rattus norvegicus |
| Biosynthesis of DPAn-3 SPMs | Rattus norvegicus |
| Biosynthesis of EPA-derived SPMs | Rattus norvegicus |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | Rattus norvegicus |
| Nicotinamide salvaging | Rattus norvegicus |
| Synthesis of 15-eicosatetraenoic acid derivatives | Rattus norvegicus |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:0080855 | Parkinsonism | |
| DOID:10247 | pleurisy | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10762 | portal hypertension | |
| DOID:10763 | hypertension | |
| DOID:10808 | gastric ulcer | |
| DOID:1184 | nephrotic syndrome | |
| DOID:12466 | secondary hyperparathyroidism | |
| DOID:12858 | Huntington's disease |
