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Interleukin-1 alpha

Summary

UniProt ID

P01583

Gene Symbol

IL1A
IL1F1

Organism

Homo sapiens (human)

External Links

PubChem: P01583

Annotation

Keyword

3D-structure
Acetylation
Cytokine
Cytoplasm
Direct protein sequencing
Glycoprotein
Mitogen
Myristate
Nucleus
Phosphoprotein
Pyrogen
Reference proteome
Secreted

Gene Ontology (GO)

Displaying entries **1 - 10** of 43 in total

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GO Term
positive regulation of transcription by RNA polymerase II
response to hypoxia
positive regulation of cytokine production
apoptotic process
inflammatory response
immune response
spermatogenesis
negative regulation of cell population proliferation
positive regulation of gene expression
positive regulation of steroid biosynthetic process

Displaying **all 5** entries
GO Term
cytosol
cell surface
extracellular region
extracellular space
nucleus

Displaying **all 3** entries
GO Term
cytokine activity
copper ion binding
interleukin-1 receptor binding

Annotation information from UniProt.

Sequence

MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
102	N-linked (GlcNAc...) asparagine			UniProt
141	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Interleukin-1 processing	Homo sapiens
Interleukin-1 signaling	Homo sapiens
Interleukin-10 signaling	Homo sapiens
Interleukin-4 and Interleukin-13 signaling	Homo sapiens
Purinergic signaling in leishmaniasis infection	Homo sapiens
Pyroptosis	Homo sapiens
Senescence-Associated Secretory Phenotype (SASP)	Homo sapiens