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pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.
- Super Class
- interstitial lung disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 623 | BDKRB1 | bradykinin receptor B1 | |
| 1131 | CHRM3 | cholinergic receptor muscarinic 3 | |
| 3552 | IL1A | interleukin 1 alpha | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 4153 | MBL2 | mannose binding lectin 2 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5328 | PLAU | plasminogen activator, urokinase | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 6439 | SFTPB | surfactant protein B | |
| 6440 | SFTPC | surfactant protein C |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O54968 | Nuclear factor erythroid 2-related factor 2 | |
| P01015 | Angiotensinogen | |
| P17246 | Transforming growth factor beta-1 proprotein | |
| P20961 | Plasminogen activator inhibitor 1 | |
| P47820 | Angiotensin-converting enzyme |
