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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tissue factor pathway inhibitor
Summary
- UniProt ID
- P10646
- Gene Symbol
-
- TFPI
- LACI
- TFPI1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011473
- GlyConnect
- GlyGen
- P10646
- PubChem
- P10646
- RaftProt
- P10646
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood coagulation
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Microsome
- Reference proteome
- Repeat
- Secreted
- Serine protease inhibitor
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to steroid hormone stimulus |
| blood coagulation |
| negative regulation of blood coagulation |
| GO Term |
|---|
| endoplasmic reticulum |
| cell surface |
| side of membrane |
| extracellular region |
| extracellular space |
| plasma membrane |
| caveola |
| GO Term |
|---|
| endopeptidase inhibitor activity |
| serine-type endopeptidase inhibitor activity |
- Site Annotations
| Position | Description |
|---|---|
| 256 | Not glycosylated |
Sequence
MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIFVKNM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 42 | O-linked (GalNAc...) threonine; partial | |||
| 112 |
|
|||
| 115 |
|
|||
| 116 |
|
|||
| 145 | N-linked (GlcNAc...) asparagine | |||
| 195 | N-linked (GlcNAc...) asparagine | |||
| 202 | O-linked (GalNAc...) serine; partial | |||
| 203 | O-linked (GalNAc...) threonine | |||
| 256 |
|
|||
|
|
G43417UB
G57321FI
G51562OR
G70232NH
G31991IV
G07947TY
G63889NK
G65832JS
G45395BF
G14972EH
G43223CG
G00912UN
G45359RY
G86357DX
G87661QW
G83646BJ
G27058EU
G83460ZZ
G41071NU
G80920RR
G78059CC
G62765YT
G10486CT
G90734RJ
G31852PQ
G41247ZX
G50282JC
G02815KT
G84349RE
G83633GK
G49632WD
G29068FM
G70894RY
G31544HA
G90093AU
G72797UR
G24413UY
G43984TE
G46422KL
G49743VF
G57196QI
G32673DL
G45700OA
G23863VK
G29931IJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Extrinsic Pathway of Fibrin Clot Formation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
