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MIRAGE
Angiotensinogen
Summary
- UniProt ID
- P01015
- Gene Symbol
-
- Agt
- Serpina8
- Gene ID
- 24179
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Vasoconstrictor
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| type 1 angiotensin receptor binding |
| type 2 angiotensin receptor binding |
| serine-type endopeptidase inhibitor activity |
| hormone activity |
Sequence
MTPTGAGLKATIFCILTWVSLTAGDRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (i) signalling events | Rattus norvegicus |
| G alpha (q) signalling events | Rattus norvegicus |
| Metabolism of Angiotensinogen to Angiotensins | Rattus norvegicus |
| Peptide ligand-binding receptors | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:10763 | hypertension | |
| DOID:10808 | gastric ulcer | |
| DOID:11446 | sciatic neuropathy | |
| DOID:1875 | impotence | |
| DOID:1936 | atherosclerosis | |
| DOID:3770 | pulmonary fibrosis | |
| DOID:5844 | myocardial infarction | |
| DOID:6432 | pulmonary hypertension | |
| DOID:8947 | diabetic retinopathy |
