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MIRAGE
Pulmonary surfactant-associated protein B
Summary
- UniProt ID
- P07988
- Gene Symbol
-
- SFTP3
- SFTPB
- Gene ID
- 6439
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Signal
- Surface film
- Gene Ontology (GO)
| GO Term |
|---|
| sphingolipid metabolic process |
| respiratory gaseous exchange by respiratory system |
| animal organ morphogenesis |
Sequence
MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective CSF2RA causes SMDP4 | Homo sapiens |
| Defective CSF2RB causes SMDP5 | Homo sapiens |
| Defective pro-SFTPB causes SMDP1 and RDS | Homo sapiens |
| Surfactant metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11162 | respiratory failure | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11650 | bronchopulmonary dysplasia | |
| DOID:12120 | pulmonary alveolar proteinosis | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:1273 | respiratory syncytial virus infectious disease | |
| DOID:14115 | toxic shock syndrome | |
| DOID:3082 | interstitial lung disease | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3770 | pulmonary fibrosis |
