cytochrome P450 family 19 subfamily A member 1

Summary
Gene Symbol
  • CYP19A1
Aliases
  • ARO
  • ARO1
  • CPV1
  • CYAR
  • P-450AROM
  • aromatase
Organism
Homo sapiens (human)
External Links
NCBI Gene
1588
HGNC
2594
KEGG Gene ID
hsa:1588
PubChem
1588
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Disease variant
  • Heme
  • Lipid metabolism
  • Microsome
  • Monooxygenase
  • Pseudohermaphroditism
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying all 5 entries
UniProt Protein Name
A8K6W3
  • CYPXIX
  • Cytochrome P-450AROM
  • Cytochrome P450 19A1
  • Estrogen synthase
Q8IYG4
  • CYPXIX
  • Cytochrome P-450AROM
  • Cytochrome P450 19A1
  • Estrogen synthase
P11511
  • CYPXIX
  • Cytochrome P-450AROM
  • Cytochrome P450 19A1
  • Estrogen synthase
Q8TCA4
Q05CU4
  • CYPXIX
  • Cytochrome P450 19A1
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000137869

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K07434
Name
aromatase [EC:1.14.14.14]
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 401 in total
DO ID Disease Name Source
DOID:0050328 congenital hypothyroidism
DOID:0050457 Sertoli cell-only syndrome
DOID:0050471 Carney complex
DOID:0050572 cone-rod dystrophy
DOID:0050589 inflammatory bowel disease
DOID:0050646 distal arthrogryposis
DOID:0050741 alcohol dependence
DOID:0050782 Zollinger-Ellison syndrome
DOID:0050811 congenital adrenal hyperplasia
DOID:0060041 autism spectrum disorder
The Human Phenotype Ontology
Displaying entries 1 - 10 of 32 in total
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0000007 Autosomal recessive inheritance
HP:0000028 Cryptorchidism
HP:0000061 Ambiguous genitalia, female
HP:0000098 Tall stature
HP:0000138 Ovarian cyst
HP:0000771 Gynecomastia
HP:0000786 Primary amenorrhea
HP:0000815 Hypergonadotropic hypogonadism
HP:0000855 Insulin resistance
Displaying all 3 entries
Disease ID Disease Name
OMIM:139300
  • aromatase excess syndrome
OMIM:613546
  • aromatase deficiency
ORPHA:91
  • aromatase deficiency
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP001780
Gene Name
cytochrome P450, family 19, subfamily A, polypeptide 1

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.0.0

Last updated: August 19, 2024