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Submissions

cytochrome P450 family 11 subfamily B member 2

Summary

Gene Symbol

CYP11B2

Organism

Mandrillus leucophaeus (drill)

External Links

NCBI Gene: 105536288
KEGG Gene ID: mleu:105536288
PubChem: 105536288

Annotation

Keyword

Heme
Membrane
Monooxygenase
Reference proteome
Steroidogenesis
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5ZYX0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cellular response to peptide hormone stimulus	IEA	30032202
glucocorticoid biosynthetic process	IEA	30032202
aldosterone biosynthetic process	IEA	30032202
cortisol metabolic process	IEA	30032202
cholesterol metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

aldosterone biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

olefinic compound biosynthetic process [inference]

aldosterone biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

cellular ketone metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

tertiary alcohol metabolic process [inference]

cortisol metabolic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

cellular ketone metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

aldosterone biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

cellular ketone metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

olefinic compound metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

olefinic compound biosynthetic process [inference]

aldosterone biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

glucocorticoid metabolic process [inference]

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

olefinic compound biosynthetic process [inference]

aldosterone biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

glucocorticoid biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

tertiary alcohol metabolic process [inference]

cortisol metabolic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

aldosterone biosynthetic process

cellular process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

cellular ketone metabolic process [inference]

aldosterone metabolic process [inference]

aldosterone biosynthetic process

cortisol metabolic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

cellular biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

ketone biosynthetic process [inference]

aldosterone biosynthetic process

aldehyde biosynthetic process [inference]

aldosterone biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

C21-steroid hormone metabolic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

mineralocorticoid metabolic process [inference]

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

aldosterone metabolic process [inference]

aldosterone biosynthetic process

hormone biosynthetic process [inference]

C21-steroid hormone biosynthetic process [inference]

aldosterone biosynthetic process

mineralocorticoid biosynthetic process [inference]

aldosterone biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IEA	30032202
mitochondrion	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
steroid 11-beta-monooxygenase activity	IEA	30032202
corticosterone 18-monooxygenase activity	IEA	30032202
iron ion binding	IEA	22301074
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

steroid hydroxylase activity [inference]

steroid 11-beta-monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07433

Name

steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]

References

Rhea

RHEA:15629

H⁺ + O₂ + a steroid

H₂O + an 11β-hydroxysteroid

Enzyme

1.14.15.4

PMID

Ortholog

Displaying entries **11 - 20** of 57 in total

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Balaenoptera musculus	118883237	BALMU01192
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Equus caballus	100063612	HORSE42961

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements