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Standards Ontologies Notations
ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Summary
Gene Symbol
  • ST3GAL1
Organism
Cercocebus atys (sooty mangabey)
NCBI Gene
105588352
KEGG Gene ID
caty:105588352
PubChem
105588352
Annotation
Keyword
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
A0A2K5L7V5
  • Gal-NAc6S
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
  • ST3Gal I
  • ST3GalA.1
  • ST3O
  • Sialyltransferase 4A
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Cercopithecoidea
Group Name
CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1
Functional Category
  • G: Carbohydrate transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
ganglioside biosynthetic process via lactosylceramide
memory B cell differentiation
negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process
sialylation
sialyltransferase activity
transferase activity
Displaying all 3 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
Sialyltransferase
KEGG BRITE Database
Orthology
K00780
Name
beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]
References
Reactions
Displaying all 5 entries
KEGG Reaction Enzyme Acceptor Product
R05949
R05942
R05957
R05967
R05913
Rhea

RHEA:52380

a β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID

RHEA:18021

CMP-N-acetyl-β-neuraminate + a ganglioside GM1 (d18:1(4E))
H+ + CMP + a ganglioside GD1a (d18:1(4E))
Enzyme
PMID

RHEA:21616

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 21 - 30 of 70 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
101016088 9555_0:00234f PAPAN38259
101039394 SAIBB22683
101122606 SHEEP19113
101152668 GORGO41056
101326842 TURTR08337
101575385 OCTDE20899
101594650 JACJA07648
101675267 MUSPF17253
101790636 ANAPL00935
101811246 FICAL02823
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024