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trans-2,3-enoyl-CoA reductase

Summary

Gene Symbol

Tecr

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

106529

PubChem

106529

Alliance of Genome Resources

MGI:1915408

Annotation

Keyword

Acetylation
Endoplasmic reticulum
Fatty acid biosynthesis
Glycoprotein
NADP
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Sphingolipid metabolism
Steroid biosynthesis
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9CY27	Synaptic glycoprotein SC2 Trans-2,3-enoyl-CoA reductase
G3UWE1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
fatty acid elongation	ISO ISS
very long-chain fatty acid biosynthetic process	IBA ISO ISS
steroid biosynthetic process	IEA
sphingolipid metabolic process	IEA ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISO ISS
endoplasmic reticulum	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IBA
very-long-chain enoyl-CoA reductase activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

very-long-chain enoyl-CoA reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

very-long-chain enoyl-CoA reductase

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
fatty acid metabolic process
lipid metabolic process
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity
very long-chain fatty acid biosynthetic process
very-long-chain enoyl-CoA reductase activity

Displaying **all 4** entries
InterPro
3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
TECR-like, N-terminal domain
Ubiquitin-like domain superfamily

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050889	non-syndromic intellectual disability	Alliance of Genome Resources
DOID:0081188	autosomal recessive intellectual developmental disorder 14	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **102** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9524		HGNC:4551	HUMAN41421
Drosophila melanogaster	38457		FB:FBgn0035471
Caenorhabditis elegans	174140		WB:WBGene00000198
Rattus norvegicus	191576	10116_1:0050ea	RGD:620376	RATNO15037
Danio rerio	326954		ZFIN:ZDB-GENE-030131-5154	DANRE17169
Pan troglodytes	455786			PANTR17419
Xenopus tropicalis	493561		Xenbase:XB-GENE-1003054
Rattus norvegicus	499018	10116_1:000bde		RATNO15037
Danio rerio	566085		ZFIN:ZDB-GENE-090930-1
Bos taurus	614105			BOVIN32421