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trans-2,3-enoyl-CoA reductase

Summary

Gene Symbol

Tecr

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

106529

PubChem

106529

Alliance of Genome Resources

MGI:1915408

Annotation

Keyword

Acetylation
Endoplasmic reticulum
Fatty acid biosynthesis
Glycoprotein
NADP
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Sphingolipid metabolism
Steroid biosynthesis
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9CY27	Synaptic glycoprotein SC2 Trans-2,3-enoyl-CoA reductase
G3UWE1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
fatty acid elongation	ISO ISS
very long-chain fatty acid biosynthetic process	IBA ISO ISS
steroid biosynthetic process	IEA
sphingolipid metabolic process	IEA ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

steroid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISO ISS
endoplasmic reticulum	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IBA
very-long-chain enoyl-CoA reductase activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

very-long-chain enoyl-CoA reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

very-long-chain enoyl-CoA reductase

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
fatty acid metabolic process
lipid metabolic process
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity
very long-chain fatty acid biosynthetic process
very-long-chain enoyl-CoA reductase activity

Displaying **all 4** entries
InterPro
3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
TECR-like, N-terminal domain
Ubiquitin-like domain superfamily

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050889	non-syndromic intellectual disability	Alliance of Genome Resources
DOID:0081188	autosomal recessive intellectual developmental disorder 14	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **102** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	851547		SGD:S000002173
Monodelphis domestica	100026440			MONDO19977
Callithrix jacchus	100402213			CALJA24252
Pongo abelii	100440904			PONAB14302
Sus scrofa	100515709			PIGXX18220
Ictalurus punctatus	100528865			ICTPU21582
Anolis carolinensis	100566730			ANOCA02927
Nomascus leucogenys	100581652			NOMLE00393
Oreochromis niloticus	100701654			ORENI62395
Cavia porcellus	100714067	10141_0:000506		CAVPO24184