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Braf transforming gene
Summary
- Gene Symbol
-
- Braf
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Allosteric enzyme
- Alternative splicing
- Cell membrane
- Chromosomal rearrangement
- Cytoplasm
- Isopeptide bond
- Metal-binding
- Methylation
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P28028 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to xenobiotic stimulus | ||
| positive regulation of stress fiber assembly | ||
| substrate adhesion-dependent cell spreading | ||
| ERK1 and ERK2 cascade | ||
| thymus development |
GO Hierarchy
- regulation of cell population proliferation
biological process
metabolic process
cellular process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| scaffold protein binding | ||
| protein serine/threonine kinase activity | ||
| mitogen-activated protein kinase kinase binding | ||
| protein serine kinase activity |
|
|
| calcium ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0060233 | cardiofaciocutaneous syndrome | |
| DOID:0060585 | Noonan syndrome 7 | |
| DOID:0080550 | Noonan syndrome with multiple lentigines 3 | |
| DOID:0111460 | cardiofaciocutaneous syndrome 1 | |
| DOID:1324 | lung cancer | |
| DOID:1520 | colon carcinoma | |
| DOID:162 | cancer | |
| DOID:1793 | pancreatic cancer |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100469346 | AILME10304 | ||
| 101671970 | MUSPF17961 | ||
| 101092346 | FELCA04744 | ||
| 122212673 | PANLE22337 | ||
| 101327462 | TURTR05195 | ||
| 118900685 | BALMU11960 | ||
| 100065760 | HORSE32563 | ||
| 536051 | BOVIN28548 | ||
| 102174360 | CAPHI23260 | ||
| 101107438 | SHEEP15773 |
