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anti-Mullerian hormone type 2 receptor

Summary

Gene Symbol

Amhr2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110542

PubChem

110542

Alliance of Genome Resources

MGI:105062

Annotation

Keyword

ATP-binding
Disulfide bond
Glycoprotein
Magnesium
Manganese
Metal-binding
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K592	Anti-Muellerian hormone type II receptor MIS type II receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway	ISO TAS	8895659
protein phosphorylation	IEA
male gonad development	IEA
anti-Mullerian hormone signaling pathway	ISO ISS
sex differentiation	IMP	8895659

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

gonad development [inference]

reproductive structure development [inference]

gonad development [inference]

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
receptor complex	IBA
plasma membrane	IBA ISO TAS	11960012 8895659

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
protein homodimerization activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

hormone binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

protein-hormone receptor activity [inference]

anti-Mullerian hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

anti-Muellerian hormone type-2 receptor

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity
transforming growth factor beta receptor activity
transmembrane receptor protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase signaling pathway

Displaying **all 6** entries
InterPro
Anti-muellerian hormone receptor, type II
Protein kinase domain
Protein kinase-like domain superfamily
Ser/Thr protein kinase, TGFB receptor
Serine-threonine/tyrosine-protein kinase, catalytic domain
Snake toxin-like superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050791	persistent Mullerian duct syndrome	Alliance of Genome Resources
DOID:1967	leiomyosarcoma	Alliance of Genome Resources
DOID:4441	dysgerminoma	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 77 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Octodon degus	101591943	10160_0:002d87
Jaculus jaculus	101594315	51337_0:001f1d	JACJA00875
Mustela putorius furo	101679847		MUSPF03918
Heterocephalus glaber	101698756	10181_0:004986
Mesocricetus auratus	101825305	10036_0:00289a
Ictidomys tridecemlineatus	101955968	43179_0:000908	ICTTR08474
Microtus ochrogaster	101989760	79684_0:001f06
Chinchilla lanigera	102020884	34839_0:002d64	CHILA14779
Macaca fascicularis	102117592		MACFA03254
Myotis lucifugus	102420471		MYOLU09502