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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic alpha 2 subunit
Summary
- Gene Symbol
-
- CHRNA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15822 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synaptic transmission, cholinergic | ||
| modulation of inhibitory postsynaptic potential | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine-gated channel complex | ||
| nucleoplasm | ||
| intercellular bridge | ||
| synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| heterocyclic compound binding | ||
| quaternary ammonium group binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060685 | autosomal dominant nocturnal frontal lobe epilepsy 4 | |
| DOID:0081119 | benign familial infantile seizures 6 | |
| DOID:1574 | alcohol use disorder | |
| DOID:3635 | congenital myasthenic syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 712868 | MACMU44312 | |||
| 100030589 | MONDO07873 | |||
| 100091849 | ORNAN29854 | |||
| 100350470 | RABIT08101 | |||
| 100403598 | CALJA08798 | |||
| 100451356 | 9601_0:0024d4 | PONAB34130 | ||
| 100483822 | AILME17651 | |||
| 100495873 | Xenbase:XB-GENE-1013893 | |||
| 100585295 | NOMLE35844 | |||
| 100734964 | CAVPO00832 |
