Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic alpha 2 subunit
Summary
- Gene Symbol
-
- CHRNA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15822 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synaptic transmission, cholinergic | ||
| modulation of inhibitory postsynaptic potential | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine-gated channel complex | ||
| nucleoplasm | ||
| intercellular bridge | ||
| synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| heterocyclic compound binding | ||
| quaternary ammonium group binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060685 | autosomal dominant nocturnal frontal lobe epilepsy 4 | |
| DOID:0081119 | benign familial infantile seizures 6 | |
| DOID:1574 | alcohol use disorder | |
| DOID:3635 | congenital myasthenic syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 103730030 | NANGA09629 | |||
| 104673969 | RHIRO09876 | |||
| 105482018 | MACNE24502 | |||
| 105542345 | MANLE18251 | |||
| 105579175 | CERAT15292 | |||
| 105705330 | AOTNA10261 | |||
| 105825243 | PROCO10424 | |||
| 105877170 | MICMU10331 | |||
| 106832512 | EQUAS22136 | |||
| 108717255 | Xenbase:XB-GENE-17340371 |
