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MIRAGE
cholinergic receptor nicotinic beta 3 subunit
Summary
- Gene Symbol
-
- CHRNB3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q05901 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| signal transduction | ||
| synaptic transmission, cholinergic | ||
| neuromuscular synaptic transmission | ||
| ion transmembrane transport | ||
| monoatomic ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| acetylcholine-gated channel complex | ||
| membrane | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity |
|
|
| channel activity | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| acetylcholine binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acetylcholine receptor subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:14330 | Parkinson's disease | |
| DOID:1596 | depressive disorder | |
| DOID:3312 | bipolar disorder | |
| DOID:9975 | cocaine dependence |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1134 | FB:FBgn0266347 | ||
| 1135 | FB:FBgn0266347 | ||
| 1136 | FB:FBgn0266347 | ||
| 1137 | FB:FBgn0266347 | ||
| 1138 | FB:FBgn0266347 | ||
| 1140 | FB:FBgn0266347 | ||
| 1141 | FB:FBgn0266347 | ||
| 1142 | Xenbase:XB-GENE-5793509 | ||
| 1143 | WB:WBGene00000043 | ||
| 1144 | FB:FBgn0266347 |
