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MIRAGE
Neuronal acetylcholine receptor subunit beta-3

Summary
UniProt ID
Q05901
Gene Symbol
  • CHRNB3
Gene ID
1142
Organism
Homo sapiens (human)
PubChem
Q05901
The Human Metabolome Database
HMDBP12052
Re-Glyco
Q05901
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • Ligand-gated ion channel
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 8 entries
GO Term
plasma membrane
membrane
neuron projection
synapse
postsynaptic membrane
presynapse
acetylcholine-gated channel complex
dopaminergic synapse
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MLPDFMLVLIVLGIPSSATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDHVDRYSSPEKEESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
51 N-linked (GlcNAc...) asparagine
138 N-linked (GlcNAc...) asparagine
166 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Highly calcium permeable nicotinic acetylcholine receptors Homo sapiens
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Homo sapiens
Disease
Displaying all 6 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:14330 Parkinson's disease
DOID:1596 depressive disorder
DOID:3312 bipolar disorder
DOID:9975 cocaine dependence
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025