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brain derived neurotrophic factor

Summary

Gene Symbol

Bdnf

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12064

PubChem

12064

Alliance of Genome Resources

MGI:88145

Annotation

Keyword

Alternative splicing
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q541P3
P21237

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 65 in total

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GO Term	Evidence Code	PMID
negative regulation of synaptic transmission, GABAergic	IDA	16754670
nerve growth factor signaling pathway	IBA
regulation of retinal cell programmed cell death	IDA	11747369
positive regulation of neuron projection development	IGI	26708520
behavioral fear response	IMP	15249684

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

retrograde trans-synaptic signaling [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by BDNF [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling, modulating synaptic transmission [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

synaptic signaling via neuropeptide [inference]

trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

axon target recognition

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

neurotrophin signaling pathway [inference]

nerve growth factor signaling pathway

cell recognition [inference]

neuron recognition

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cell growth [inference]

developmental cell growth [inference]

collateral sprouting

neuron projection extension

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

peptidyl-serine phosphorylation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

mechanoreceptor differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendrite development

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

export from cell [inference]

secretion by cell [inference]

glutamate secretion

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

learning

associative learning [inference]

conditioned place preference

behavior [inference]

behavioral defense response [inference]

behavioral fear response

learning or memory

learning

associative learning [inference]

conditioned place preference

feeding behavior

adult behavior [inference]

behavioral response to cocaine

multicellular organismal response to stress [inference]

fear response

behavioral fear response

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

kidney epithelium development [inference]

mesonephric epithelium development [inference]

mesonephric tubule development [inference]

ureteric bud development

tube development [inference]

mesonephric tubule development [inference]

ureteric bud development

animal organ development [inference]

sensory organ development [inference]

taste bud development

system development [inference]

nervous system development

inner ear development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

mechanoreceptor differentiation

growth [inference]

cell growth [inference]

developmental cell growth [inference]

collateral sprouting

neuron projection extension

developmental growth [inference]

developmental cell growth [inference]

collateral sprouting

neuron projection extension

developmental growth involved in morphogenesis [inference]

collateral sprouting

neuron projection extension

rhythmic process [inference]

circadian rhythm

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response

behavioral fear response

response to chemical [inference]

response to acid chemical [inference]

cellular response to acid chemical

response to xenobiotic stimulus

cellular response to chemical stimulus [inference]

cellular response to acid chemical

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to acid chemical

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

glutamate secretion

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

nitrogen compound transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

amide transport [inference]

glutamate secretion

export from cell [inference]

secretion by cell [inference]

glutamate secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of glucocorticoid receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, GABAergic [inference]

negative regulation of synaptic transmission, GABAergic

regulation of synaptic plasticity

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

positive regulation of long-term neuronal synaptic plasticity

regulation of short-term neuronal synaptic plasticity

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

trans-synaptic signaling, modulating synaptic transmission [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

retrograde trans-synaptic signaling [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by BDNF [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling, modulating synaptic transmission [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

synaptic signaling via neuropeptide [inference]

trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

regulation of extent of cell growth [inference]

regulation of axon extension

positive regulation of axon extension

regulation of collateral sprouting

positive regulation of collateral sprouting

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of developmental growth [inference]

regulation of developmental growth [inference]

regulation of axon extension

positive regulation of axon extension

positive regulation of developmental growth [inference]

regulation of collateral sprouting

positive regulation of collateral sprouting

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of developmental growth [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

positive regulation of cell growth [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of axonogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

positive regulation of developmental growth [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

negative regulation of programmed cell death

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle tissue development [inference]

negative regulation of striated muscle tissue development

negative regulation of multicellular organismal process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of glucocorticoid receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

regulation of collateral sprouting

positive regulation of collateral sprouting

positive regulation of axonogenesis [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

regulation of striated muscle cell differentiation [inference]

regulation of myotube differentiation [inference]

negative regulation of myotube differentiation

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

regulation of retinal cell programmed cell death

regulation of muscle organ development [inference]

regulation of striated muscle tissue development [inference]

negative regulation of striated muscle tissue development

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

regulation of developmental growth [inference]

regulation of axon extension

positive regulation of axon extension

positive regulation of developmental growth [inference]

regulation of collateral sprouting

positive regulation of collateral sprouting

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle tissue development [inference]

negative regulation of striated muscle tissue development

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

positive regulation of developmental growth [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

regulation of muscle tissue development [inference]

regulation of striated muscle tissue development [inference]

negative regulation of striated muscle tissue development

negative regulation of muscle tissue development [inference]

negative regulation of striated muscle tissue development

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

neurotrophin signaling pathway [inference]

nerve growth factor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of glucocorticoid receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, GABAergic [inference]

negative regulation of synaptic transmission, GABAergic

regulation of synaptic plasticity

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

positive regulation of long-term neuronal synaptic plasticity

regulation of short-term neuronal synaptic plasticity

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

trans-synaptic signaling, modulating synaptic transmission [inference]

trans-synaptic signaling by BDNF, modulating synaptic transmission

trans-synaptic signaling by neuropeptide, modulating synaptic transmission [inference]

retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

negative regulation of apoptotic process

regulation of neuron apoptotic process

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

negative regulation of programmed cell death

negative regulation of apoptotic process

regulation of retinal cell programmed cell death

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

regulation of muscle cell differentiation [inference]

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

regulation of striated muscle cell differentiation [inference]

regulation of myotube differentiation [inference]

negative regulation of myotube differentiation

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of glucocorticoid receptor signaling pathway

positive regulation of cell growth [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of neuron differentiation

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of axonogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of neural precursor cell proliferation [inference]

negative regulation of neuroblast proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission [inference]

negative regulation of synaptic transmission, GABAergic

negative regulation of programmed cell death

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

negative regulation of muscle cell differentiation [inference]

negative regulation of striated muscle cell differentiation [inference]

negative regulation of myotube differentiation

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

regulation of extent of cell growth [inference]

regulation of axon extension

positive regulation of axon extension

regulation of collateral sprouting

positive regulation of collateral sprouting

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of axonogenesis [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

regulation of axonogenesis [inference]

regulation of collateral sprouting

positive regulation of collateral sprouting

positive regulation of axonogenesis [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of axonogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of long-term neuronal synaptic plasticity

positive regulation of axonogenesis [inference]

positive regulation of synapse assembly

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

regulation of synaptic plasticity

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

positive regulation of long-term neuronal synaptic plasticity

regulation of short-term neuronal synaptic plasticity

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of binding [inference]

positive regulation of protein binding [inference]

positive regulation of receptor binding

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

regulation of binding [inference]

regulation of protein binding [inference]

positive regulation of protein binding [inference]

positive regulation of receptor binding

regulation of receptor binding [inference]

positive regulation of receptor binding

positive regulation of binding [inference]

positive regulation of protein binding [inference]

positive regulation of receptor binding

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
cytoplasmic vesicle	IDA	14715936 15242649
hippocampal mossy fiber to CA3 synapse	IDA	22412021
glutamatergic synapse	EXP IDA	19448629
axon	IBA IDA ISO	19448629
synaptic vesicle	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

mitochondrial crista

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

perinuclear region of cytoplasm

presynapse [inference]

terminal bouton

postsynapse

Displaying **all 4** entries
GO Term	Evidence Code	PMID
growth factor activity	IBA IEA
neurotrophin TRKB receptor binding	ISO	1649702
protein binding	IPI	11684666 24573299
nerve growth factor receptor binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

neurotrophin receptor binding [inference]

nerve growth factor receptor binding

neurotrophin TRK receptor binding [inference]

neurotrophin TRKB receptor binding

tumor necrosis factor receptor superfamily binding [inference]

death receptor binding [inference]

nerve growth factor receptor binding

receptor ligand activity [inference]

growth factor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Brain-derived neurotrophic factor

Functional Category

Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

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Gene Ontology
growth factor activity
memory
modulation of chemical synaptic transmission
negative regulation of neuron apoptotic process
nerve development
nerve growth factor receptor binding
nerve growth factor signaling pathway
neuron projection morphogenesis
peripheral nervous system development
positive regulation of collateral sprouting

Displaying **all 5** entries
InterPro
Brain-derived neurotrophic factor
Cystine-knot cytokine
Nerve growth factor conserved site
Nerve growth factor-like
Nerve growth factor-related

Disease

Disease Ontology

Displaying entries **1 - 10** of 58 in total

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DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources
DOID:0050848	obstructive sleep apnea	Alliance of Genome Resources
DOID:0060001	withdrawal disorder	Alliance of Genome Resources
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0060731	congenital central hypoventilation syndrome	Alliance of Genome Resources
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:10126	keratoconus	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1070	primary open angle glaucoma	Alliance of Genome Resources
DOID:10914	amnestic disorder	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	627		HGNC:1033	HUMAN05100
Rattus norvegicus	24225	10116_1:001655	RGD:2202	RATNO27066
Danio rerio	58118		ZFIN:ZDB-GENE-000412-1	DANRE39504
Sus scrofa	397495			PIGXX17500
Felis catus	493690			FELCA24057
Pan troglodytes	503511			PANTR02543
Monodelphis domestica	554233			MONDO28037
Bos taurus	617701			BOVIN07322
Macaca mulatta	701245			MACMU09565
Taeniopygia guttata	751584			TAEGU25191

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements