GlyCosmos Portal

Submissions

GRB2 associated binding protein family member 4

Summary

Gene Symbol

GAB4

Organism

Homo sapiens (human)

External Links

NCBI Gene

128954

PubChem

128954

Alliance of Genome Resources

HGNC:18325

Annotation

Keyword

Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2WGN9	GRB2-associated binder 2-like GRB2-associated binder 4 GRB2-associated-binding protein 2-like Growth factor receptor bound protein 2-associated protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signal transduction	IBA
transmembrane receptor protein tyrosine kinase signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
transmembrane receptor protein tyrosine kinase adaptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor tyrosine kinase binding [inference]

transmembrane receptor protein tyrosine kinase adaptor activity

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding [inference]

transmembrane receptor protein tyrosine kinase adaptor activity

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity [inference]

signaling receptor complex adaptor activity [inference]

transmembrane receptor protein tyrosine kinase adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

grb2-associated-binding protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
signaling adaptor activity

Displaying **all 3** entries
InterPro
GRB2-associated-binding protein 1-4-like
PH-like domain superfamily
Pleckstrin homology domain

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	2549	FB:FBgn0016794
Drosophila melanogaster	14388	FB:FBgn0016794
Xenopus tropicalis	128954	Xenbase:XB-GENE-494700
Pan troglodytes	470133		PANTR25891
Macaca mulatta	100425935		MACMU01674
Nomascus leucogenys	100591714		NOMLE34636
Pan paniscus	100968366		PANPA23244
Gorilla gorilla gorilla	101137474		GORGO23847