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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
a disintegrin and metallopeptidase domain 28
Summary
- Gene Symbol
-
- Adam28
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9JLN6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| cell surface | ||
| mitochondrion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| immunoglobulin receptor binding | ||
| metal ion binding | ||
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Zinc finger, RING-type
- Functional Category
-
- C: Energy production and conversion
- G: Carbohydrate transport and metabolism
- K: Transcription
- L: Replication, recombination and repair
| Gene Ontology |
|---|
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain |
| Peptidase M12B, ADAM/reprolysin |
| Peptidase M12B, propeptide |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060075 | estrogen-receptor positive breast cancer | |
| DOID:1612 | breast cancer | |
| DOID:3008 | invasive ductal carcinoma | |
| DOID:3459 | breast carcinoma | |
| DOID:3571 | liver cancer | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:7596 | asbestos-related lung carcinoma | |
| DOID:9256 | colorectal cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 10863 | HGNC:206 | HUMAN93043 | ||
| 181489 | WB:WBGene00000074 | |||
| 290344 | 10116_1:0045b2 | RGD:727820 | RATNO10246 | |
| 464061 | PANTR42184 | |||
| 505890 | BOVIN34757 | |||
| 608753 | CANLF09988 | |||
| 710953 | MACMU43893 | |||
| 767749 | ZFIN:ZDB-GENE-060929-532 | |||
| 3772109 | FB:FBgn0265140 | |||
| 100145537 | Xenbase:XB-GENE-5949648 |
