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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate-cysteine ligase, catalytic subunit
Summary
- Gene Symbol
-
- Gclc
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Glutathione biosynthesis
- Ligase
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to activity |
|
|
| response to heat | ||
| negative regulation of transcription, DNA-templated | ||
| negative regulation of hepatic stellate cell activation | ||
| negative regulation of DNA-templated transcription |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-cysteine ligase complex | ||
| cytosol | ||
| mitochondrion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-containing complex binding | ||
| glutamate binding | ||
| ADP binding | ||
| nucleotide binding |
Disease
- Disease Ontology
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 710508 | MACMU34523 | ||
| 105490843 | MACNE33999 | ||
| 101006397 | PAPAN33822 | ||
| 105540597 | MANLE14252 | ||
| 101128718 | GORGO37350 | ||
| 100995141 | PANPA34632 | ||
| 742732 | PANTR38416 | ||
| 100454425 | PONAB30471 | ||
| 2729 | HGNC:4311 | HUMAN85231 | |
| 609822 | CANLF02862 |
