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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate-cysteine ligase, catalytic subunit
Summary
- Gene Symbol
-
- Gclc
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Glutathione biosynthesis
- Ligase
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood vessel diameter maintenance | ||
| cellular response to glucose stimulus |
|
|
| glutamate metabolic process | ||
| negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | ||
| negative regulation of extrinsic apoptotic signaling pathway |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-cysteine ligase complex | ||
| cytosol | ||
| mitochondrion |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| catalytic activity | ||
| magnesium ion binding | ||
| ligase activity | ||
| glutamate-cysteine ligase activity | ||
| ATP binding |
Disease
- Disease Ontology
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102180090 | CAPHI15900 | ||
| 101114822 | SHEEP10132 | ||
| 100342383 | RABIT02544 | ||
| 105987708 | DIPOR13428 | ||
| 25283 | RGD:619868 | RATNO41217 | |
| 100726181 | CAVPO18013 | ||
| 101567172 | OCTDE23431 | ||
| 101869677 | MELUD02070 | ||
| 100014379 | MONDO14177 | ||
| 102462808 | PELSI14284 |
