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neurocan

Summary

Gene Symbol

NCAN

Aliases

neurocan proteoglycan

Organism

Homo sapiens (human)

External Links

NCBI Gene

1463

HGNC

2465

KEGG Gene ID

hsa:1463

PubChem

1463

Alliance of Genome Resources

HGNC:2465

Annotation

Keyword

Calcium
Cell adhesion
Disulfide bond
EGF-like domain
Hyaluronic acid
Immunoglobulin domain
Lectin
Proteoglycan
Reference proteome
Repeat
Secreted
Signal
Sushi
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O14594	Chondroitin sulfate proteoglycan 3
Q4LE67

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
skeletal system development	IBA
glial cell differentiation	IBA
central nervous system development	IBA
positive regulation of neuroblast proliferation	IBA
cell adhesion	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

developmental process [inference]

anatomical structure development [inference]

system development [inference]

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region
Golgi lumen
perineuronal net	IBA
synapse	IBA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix [inference]

perisynaptic extracellular matrix [inference]

perineuronal net

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Golgi lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
hyaluronic acid binding	IEA
calcium ion binding	IEA
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000130287

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K06794

Name

neurocan core protein

References

Disease

Disease Ontology

Displaying entries **1 - 10** of 37 in total

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DO ID	Disease Name	Source
DOID:870	neuropathy	DisGeNET
DOID:936	brain disease	DisGeNET
DOID:0050635	alternating hemiplegia of childhood	DisGeNET
DOID:10588	adrenoleukodystrophy	DisGeNET
DOID:1074	kidney failure	DisGeNET
DOID:1094	attention deficit hyperactivity disorder	DisGeNET
DOID:11054	urinary bladder cancer	DisGeNET DisGeNET
DOID:11504	autonomic neuropathy	DisGeNET
DOID:11981	morbid obesity	DisGeNET
DOID:12351	alcoholic hepatitis	DisGeNET

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	407661	ZFIN:ZDB-GENE-051230-1
Danio rerio	559024	ZFIN:ZDB-GENE-050208-586
Ictalurus punctatus	108270525		ICTPU01455
Salmo salar	106573584		SALSA81941
Salmo salar	106613725		SALSA48829
Salmo trutta	115151791		SALTR114565
Oreochromis niloticus	100695628		ORENI44503
Sparus aurata	115591252		SPAAU67288
Xenopus laevis	108703703	Xenbase:XB-GENE-6488326
Xenopus laevis	108713422	Xenbase:XB-GENE-17338523

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements