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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
Summary
- Gene Symbol
-
- Grin2d
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Magnesium
- Methylation
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q03391 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to L-glutamate | ||
| regulation of presynaptic membrane potential |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| postsynaptic density membrane | ||
| NMDA selective glutamate receptor complex | ||
| plasma membrane | ||
| hippocampal mossy fiber to CA3 synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | ||
| voltage-gated monoatomic cation channel activity | ||
| monoatomic cation channel activity |
GO Hierarchy
molecular function
transporter activity [inference]
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Ionotropic glutamate receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060037 | developmental disorder of mental health | |
| DOID:0080456 | developmental and epileptic encephalopathy 46 | |
| DOID:1826 | epilepsy | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2906 | HGNC:4588 | |||
| 24412 | 10116_1:00001e | RGD:2740 | RATNO16920 | |
| 31107 | FB:FBgn0053513 | |||
| 180002 | WB:WBGene00003775 | |||
| 449864 | ZFIN:ZDB-GENE-041008-124 | |||
| 100084653 | ORNAN00743 | |||
| 100496465 | Xenbase:XB-GENE-1011863 | |||
| 100556989 | ANOCA15892 | |||
| 100731717 | 10141_0:0014f9 | |||
| 100750615 | 10029_0:003aa8 |
